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Liver disease

Category: Illnesses and disabilities

Type

Involuntary

Introduction and description

There are numerous problems that can occur with the liver that are best described under the general heading of Liver disease (also called hepatic disease). Hepatitis, for example, is inflammation of the liver and is characterised by the presence of inflamed cells in the tissue of the organ.

 

 

 

Liver and its functions

The liver has a number of very well defined functions in the body;

  • It stores minerals including iron and vitamins A, D and B1
  • It destroys worn out red blood cells
  • It manufactures plasma proteins and blood clotting agents
  • It detoxifies poisons using enzymes which break the chemicals down into less harmful products [and products which can be expelled via the faeces or urine].  Catalase for example does just this
  • It has a major role in metabolism regulating blood sugar levels – glucose may be removed from the blood and stored as glycagon or the glucose may be stored as fat or the glucose may be released into the blood stream for use as fuel – glycogen is then converted to glucose.
  • It processes fatty acids and regulates the amount of phospholipids and chloresterol, excesses are eliminated in bile and the liver produces bile.
  • It is involved in nitrogenous excretion.  The body cannot store excess proteins or amino acids, so the excess has to be eliminated.  The non nitrogenous parts are converted to fats and carbohydrates that can be used or stored.  The nitrogenous parts are converted via a series of enzyme controlled processes to urea [which needs carbon dioxide], which is then excreted via the kidneys into the urine.

Any form of damage to the liver thus has the potential to disrupt these processes. 

Symptoms

The symptoms related to liver dysfunction include some that are immediately apparent by looking at the person and yet others that are less obvious. The following relate directly to the functions above:

Mineral deficiency and vitamin deficiency - particularly deficit of fat soluble vitamins - minerals including iron and vitamins A, D and B1. From this a person may get, for example Anaemia

Mal-processing of fatty acids and irregularities of phospholipids and chloresterol, thus knock on effects of this may be

  • Indigestion and heartburn - The malabsorption of fats may lead to symptoms that include indigestion and reflux, nausea or vomiting
  • Gallstones – caused by an inability to process fatty foods
  • Cholesterol problems - elevated LDL cholesterol, reduced HDL cholesterol, elevated triglycerides
  • Atherosclerosis - clogged arteries leading to high blood pressure, heart attacks and strokes
  • Obesity - build up of fat in other body organs (fatty degeneration of organs), lumps of fat in the skin (lipomas and other fatty tumors), excessive weight gain , inability to lose weight even while dieting, abdominal bloating and pot belly

Problems handling toxins and poisons – the enzymes which normally break the harmful chemicals down into less harmful products no longer work and these can enter the body and blood stream causing numerous problems too many to list, but for example

  • Brain damage - Nervous system disorders include depression, mood changes, especially anger and irritability, poor concentration and "foggy brain", hallucinations and other experiences
  • Headaches - recurrent headaches (including migraine)
  • Cancer
  • Jaundice
  • Metabolic disorders - overheating of the body, especially the face and torso

Elevated or lowered blood sugar levels – glucose may not be removed from the blood or the glucose may not be released into the blood stream for use as fuel – weariness may result

Retention of excess proteins or amino acids.  The non nitrogenous parts are not converted to fats and carbohydrates but become toxins in the body. The nitrogenous parts are no longer converted to urea thus the wee will no longer contain these toxins. 

Skin diseases - One of the causes of skin problems can be liver damage.  People or children, for example, with a damaged liver have in studies often developed eczema/dermatitis.
“These results suggest some relationship between atopic dermatitis and liver function in infants.  PMID: 7613128”
One of the side effects of the liver damage may be that it damages the enzymes needed to process Essential Fatty Acids and this inability to process the EFAs may then result in the eczema, in the chain explained below...
Patients with atopic eczema and a mixture of allergic illnesses show biochemical evidence suggesting impairment in the desaturation of linoleic acid and linolenic acid by the enzyme delta-6 dehydrogenase. …... A distortion in the production of prostaglandins and leukotrienes, which might result from this block, can account for the immunological defects of atopy and a variety of clinical symptoms experienced by atopic individuals. Dietary supplementation with essential fatty acids relieves the signs and symptoms of atopic eczema ….PMID:  2424959
So this tells us why people with liver damage may get eczema and other skin problems.  But this is not identifying the cause of the damage, simply treating the effects, which is helpful but not enough.  To treat the eczema we have to treat the liver damage.

Causes

The causes are as follows 

Viruses - Hepatitis, inflammation of the liver, is caused mainly by various viruses (viral hepatitis).  Viral hepatitis may be caused by, for example

  • Hepatitis A, B, C, D, and E viruses
  • Yellow fever virus
  • KIs-V
  • adenoviruses

Alcohol – which is acting in the excessive doses needed for damage as a poison.

Toxins - Amanita toxin in mushrooms, carbon tetrachloride, plus numerous others.  Nanoparticles have started to become a major problem in this area.  Fungicides and pesticides can also be a problem.  Heavy metal poisoning has also been linked with liver disease.

Pharmaceuticals – which have an impressive record of damaging the liver.  The following links take you to the eHealthme web site and the pharmaceuticals which have a known record for producing various forms of liver disease, but this list is by no means complete

  • Follow this LINK for liver enlargement
  • Follow this LINK for fatty liver
  • Follow this LINK for liver injury
  • Follow this LINK for cirrhosis
  • Follow this LINK for liver disorders
  • Follow this LINK for liver pain/tenderness

Nutritional deprivation – of various sorts from Mineral deficiency and vitamin deficiency to overdosing on certain foods.  Many foods taken at overdose proportions become toxic to the liver.  Those who are allergic to certain foods such as coeliacs may find that the food to which they are allergic becomes a toxin and damages the liver

Parasites – from liver flukes to tapeworms, from toxoplasmia gondii to ascaris 

Bacteria - such as Legionella, Leptospira, Coxiella burnetii and Rickettsia rickettsii

Surgery or other forms of physical damage.  Occasionally pregnancy - because of the pressure of the foetus on the organs can cause physical damage

Hereditary damage - Hereditary diseases that cause damage to the liver include hemochromatosis, involving accumulation of iron in the body, and Wilson's disease, which causes the body to retain copper. Gilbert's syndrome, a genetic disorder of bilirubin metabolism found in about 5% of the population, can cause mild jaundice.

Fungal infection - one fungus particularly implicated in casauing very serious liver disease leading to death is aspergillus and the aflatoxin it produces

Hypoxia - see both Hypoxia and Hypoxia side-effects

Mineral supplements, Vitamin supplements and dietary supplements

Treatment

Find the cause - see also Healing yourself.

The liver is one organ which is capable of rejuvenating itself [in time] as long as it is saved from further attack.

How it works

Any one of the diseases caused by liver damage, can themselves produce spiritual experiences, however, there is one direct effect from liver damage.

Damage to the liver could result in anaemia.  Because hemoglobin (found inside red blood cells) normally carries oxygen from the lungs to the tissues, anaemia leads to hypoxia (lack of oxygen) in organs.

And here we have the reason for the spiritual experiences, this chain of reactions leads to hypoxia.

Related observations