Berberis vulgaris and Echinococcosis
Type of Spiritual Experience
Echinococcosis, also called hydatid disease, hydatidosis, or echinococcal disease, is a parasitic disease of tapeworms of the Echinococcus type. People get two main types of disease, cystic echinococcosis and alveolar echinococcosis. There are two less common forms polycystic echinococcosis and unicystic echinococcosis. The disease often starts without symptoms and this may last for a year. The symptoms and signs that occur depend on the cyst's location and size. Alveolar disease usually begins in the liver but can spread to other parts of the body such as the lungs or brain. When the liver is affected the person may have abdominal pain, weight loss, and turn yellow. Lung disease may cause pain in the chest, shortness of breath and coughing
A description of the experience
J Invest Surg. 2013 Dec;26(6):347-51. doi: 10.3109/08941939.2013.818746. Epub 2013 Aug 26. Efficacy of Berberis vulgaris aqueous extract on viability of Echinococcus granulosus protoscolices. Rouhani S1, Salehi N, Kamalinejad M, Zayeri F.
BACKGROUND: Surgery is one of the best choices for the treatment of hydatidosis. To prevent the secondary infection, it is essential to use effective scolicidal agents during surgery for hydatid cyst. Up to now, no effective and safe agent has been identified for this purpose. Berberis vulgaris called "Zereshk" in Persian has been traditionally used as a herbal remedy for the treatment of different complaints. Many studies have shown that Berberis vulgaris has antibacterial, antifungal, and antiparasitic effects.
METHODS: In our study, the scolicidal effect of barberry with different concentrations (0.5, 1, 2, and 4 mg/ml diluted form) and at different exposure times (5, 15, and 30 min) was evaluated. For this purpose, we obtained sheep liver hydatid cysts from a slaughterhouse. Viability of protoscolices was assessed by 0.1% Eosin staining. Normal saline and hypertonic saline were used as negative and positive controls, respectively.
RESULTS: All the different concentrations of Berberis vulgaris aqueous extracts had scolicidal effect. The strongest effect was observed to be in 4 mg/ml concentration, which acted as positive control. Scolicidal activity of 2 mg/ml dilution was close to 4 mg/ml and the least scolicidal effect was observed in 0.5 mg/ml. Scolicidal activity of extracts had significant differentiation between 5th and 30th min of exposure.
CONCLUSION: The scolicidal activity was very effective in low concentration (4 mg/ml) and short exposure time (5 min). Therefore, after being examined in vivo and additional experiments, it may be used as a suitable and effective scolicidal in surgery.
The source of the experiencePubMed
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