Observations placeholder

CAFFEIC-ACID

Activities

Aldose-Reductase-Inhibitor - Dosage: 4 ug/ml (weak activity) [SKN43:99]
Allergenic - [M&R317]
Analgesic - [PMP23:51]
AntiHIV - Dosage: EC50=200 ug/ml [POP:270 EMP6:189 EMP5:207]
AntiLegionella - [YAK122:487]
Antiadenoviral - [EMP5:207]
Antiaggregant - [JBH]
Antiaging - [PM69:1125]
Antiatherogenic - [X15712986]
Antibacterial - [PAM YAK122:487]
Anticancer - [JAF47:397]
Anticarcinogenic - [EMP6:189]
Antidepressant - [X12802204 X15712986]
Antiedemic - [EMP6:189]
Antielastase - Dosage: IC50=86 ug/ml (475 uM) [PM69:820] ; Dosage: IC50=93 um/l [X11199135]
Antiescherichic - [PR14:561]
Antiflu - [EMP5:207]
Antigonadotropic - [JNM1:10]
Antihemolytic - Dosage: 25 uM [PC36:579]
Antihepatoadenomic - Dosage: 200 ppm diet orl mus [ACS661:230]
Antihepatotoxic - [PM56:173]
Antiherpetic - Dosage: 50 ug/ml [V&D EMP5:206] ; Dosage: EC50=>50 ug/ml [POP:270]
Antihistaminic -
Antihypercholesterolemic - [EMP6:189]
Antihyperthyroid - [X3987612 X6724503]
Antiinflammatory - [JBH X15712986]
Antileukemic - [AJC31:37]
Antileukotriene -
Antimelanogenic - [JAF50:3718]
Antimutagenic - [PCF:18]
Antinitrosaminic - [PCF:18]
Antiophidic - [FT65(2):101]
Antioxidant - Dosage: 1.3 x Vit. E [BO2] ; Dosage: 1/2 BHA [JAF50:889] ; Dosage: 1/3 quercetin [JAF47:397] ; Dosage: 30 mM [JAF48:235] ; Dosage: 50 uM [PC27:973] ; Dosage: IC57=30 ppm [PCF:221]
Antiperoxidant - Dosage: IC35=200 ug/ml [JAF50:2993] ; Dosage: IC50=44 uM [PM57:A54] ; Dosage: IC85=100 ug/ml [X15796587]
Antiproliferant - [AJC31:37]
Antiprostaglandin - [PJB1(1):169]
Antiradicular - Dosage: 1/3 quercetin [JAF47:397] ; Dosage: 10 uM [PC36:579] ; Dosage: 30 mM [JAF48:235] ; Dosage: IC50=32-35 uM [JAF50:7022]
Antiseptic - [JE26:76]
Antispasmodic - Dosage: EC50=3.4-15 uM [PR4:73]
Antistaphylococcic - [PR14:561]
Antistomatitic - [EMP5:207]
Antisunburn - [PM61:510]
Antithiamin - [PCF:69]
Antithyroid - [JNM1:10]
Antitumor - Dosage: 200 ppm diet orl mus [ACS661:230 JAF47:397 PCF:19]
Antitumor (Skin) - [JAF50:3718]
Antitumor-Promoter - Dosage: IC42=10 uM [CR48:5941]
Antiulcerogenic - [JBH EMP6:189]
Antivaccinia - [EMP5:207]
Antiviral - Dosage: IC50=62.5 ug/ml [EMP5:253 AVR14:323]
Anxiolytic - [X12802204]
CNS-Active - [WIC]
COX-2-Inhibitor - Dosage: IC32=100 uM [JNP65:1517]
Calcium-Antagonist - Dosage: IC50=1.2 uM rbt [K16299]
Cancer-Preventive - [525]
Carcinogenic - Dosage: 2% (diet) [PCF:39 277]
Chemopreventive - [X15712986]
Cholagogue - [WIC]
Choleretic - [411]
Clastogenic - [JBH]
Co-carcinogenic - [PCF:44]
Collagen-Sparing - [PM61:510]
Cytoprotective - [CAN]
Cytotoxic - Dosage: TC50=200 ug/ml [POP:270]
DNA-Active - [JBH]
DNA-Protective - [JAF50:7022]
Diuretic - [WIC]
Fungicide - Dosage: MIC=0.4 mg/ml [PC64:211 JE26:76]
Hepatocarcinogenic - Dosage: 400 ppm diet orl mus (in the absence of alcohol) [ACS661:230]
Hepatoprotective - [ACM:210]
Hepatotropic -
Histamine-Inhibitor -
Immunostimulant - [PPL7:187]
Insectifuge - [EB48:111]
Leukotriene-Inhibitor -
Lipoxygenase-Inhibitor - Dosage: IC27=5 mM [JAF38:688] ; Dosage: IC50=62-148 uM [JAF44:2057]
Lyase-Inhibitor - Dosage: IC50=94-164 uM [JAF44:2057]
Metal-Chelator - [PCF:25]
Ornithine-Decarboxylase-Inhibitor - [PCF:19]
Pesticide -
Prooxidant - [JAFC45:632]
Prostaglandigenic - [RWG27]
Sedative - Dosage: 500 mg [RWG17]
Sunscreen - Dosage: IC50=2.5 mg/l [FT64:134] ; Dosage: IC91=5 mg/l [FT64:134] ; Dosage: IC98=25 mg/l [FT64:134]
Tumorigenic - [505]
Vulnerary - [JE26:76]
Xanthine-Oxidase-Inhibitor - Dosage: IC50=39.21 uM [MAB]