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Scientific evaluation of medicinal plants used for the treatment of abnormal uterine bleeding by Avicenna



Type of Spiritual Experience


Cuscuta chinensis Lam. is a parasitic plant in the family Convolvulaceae. It is native to China and was first described in 1786.

Portulaca oleracea (common purslane, also known as verdolaga, pigweed, little hogweed, red root, pursley, and moss rose) is an annual succulent in the family Portulacaceae, which may reach 40 cm in height.

Boswellia sacra (commonly known as frankincense or olibanum-tree) is a tree in the Burseraceae family. It is the primary tree in the genus Boswellia from which frankincense, a resinous dried sap, is harvested

Lens culinaris - is the lentil

Myrtus, with the common name myrtle, is a genus of flowering plants in the family Myrtaceae

Polygonum aviculare or common knotgrass is a plant related to buckwheat and dock. It is also called birdweed, pigweed and lowgrass. It is an annual found in fields and wasteland, with white flowers from June to October. It is widespread across many countries in temperate regions, apparently native to Eurasia and North America, naturalized in temperate parts of the Southern Hemisphere.

Pistacia lentiscus (also mastic; Greek: μαστίχα mastíkha ) is a dioecious evergreen shrub or small tree of the pistacio genus growing up to 4 m (13 ft) tall which is cultivated for its aromatic resin, mainly on the Greek island of Chios

The pomegranate, botanical name Punica granatum, is a fruit-bearing deciduous shrub or small tree growing between 5 and 8 m (16–26 ft) tall.

Ceratonia siliqua, commonly known as the carob tree, St John's-bread,  is widely cultivated for its edible pods, and as an ornamental tree in gardens. The ripe, dried pod is often ground to carob powder, which is used to replace cocoa powder. Carob bars, an alternative to chocolate bars, are often available in health-food stores.

Cuscuta epithymum (L.) L., (Dodder, Hellweed, Strangle-tare, called in Spain azafrán borde o cabellos de monte) is a parasitic plant assigned to the Cuscutaceae or Convolvulaceae family

Cydonia oblonga - is commonly known as the Quince

Solanum nigrum (European black nightshade or locally just "black nightshade", duscle, garden nightshade, "garden huckleberry", hound's berry, petty morel, wonder berry, small-fruited black nightshade or popolo) is a species in the Solanum genus, native to Eurasia and introduced in the Americas, Australasia and South Africa.

Rumex acetosa - is sorrel

A description of the experience

Arch Gynecol Obstet. 2015 Jul;292(1):21-35. doi: 10.1007/s00404-015-3629-x. Epub 2015 Jan 31.

Scientific evaluation of medicinal plants used for the treatment of abnormal uterine bleeding by Avicenna.

Mobli M1, Qaraaty M, Amin G, Haririan I, Hajimahmoodi M, Rahimi R.

PURPOSE:  Abnormal uterine bleeding (AUB) is one of the prevalent gynecological disorders that cause considerable morbidity and management of that plays an important role in protecting women's health. This review focuses on medicinal plants mentioned by Avicenna, a great Iranian philosopher and physician (A.D. 980-1037), in his book Canon for treatment of AUB.


Medicinal plants mentioned in Canon for treatment of AUB were elicited and searched in electronic databases including PubMed, Scopus, Google Scholar and Cochrane library to find studies that confirmed their efficacy. Data were collected for the years 1980-2014.


The findings included 23 plants belonging to 18 families. Scientific findings have revealed that these plants control AUB through four mechanisms of action including

  • inhibition of inflammatory process,
  • inhibition of prostaglandins production,
  • antiproliferative activity on human cervical cancer cells (HeLa), and
  • estrogenic activity.

All of the plants exhibited anti-inflammatory activity in vitro and/or in vivo.

  • Cuscuta chinensis and Portulaca oleracea exhibited estrogenic activity.
  • Boswellia carteri, Lens culinaris, Myrtus communis, Polygonum aviculare, Pistacia lentiscus, and Punica granatum have revealed inhibitory activity on biosynthesis of prostaglandins.

Some of the mentioned plants including: Ceratonia siliqua, Cuscuta chinensis, Cuscuta epithymum, Cydonia oblonga, Paeonia sp., Portulaca oleracea, Solanum nigrum, Rumex acetosa and Onopordum acanthium have shown antiproliferative activity on HeLa cells.

CONCLUSION:  Investigation of traditional Iranian medicine literatures can lead to the identification of effective natural medicines for the management of AUB; however, conclusive confirmation of the efficacy and safety of these treatments needs more evaluations.

PMID: 25637505

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