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Observations placeholder

Antibacterial activity of resin rich plant extracts

Identifier

012772

Type of Spiritual Experience

Background

  • Operculina turpethum - is a plant in the morning glory family, Operculina turpethum (syn. Ipomoea turpethum) is known commonly as turpeth, fue vao, and St. Thomas lidpod.  It is endemic to India. It is commonly found in North Circars and Deccan region up to 3000 ft. It is also known as: Indian Jalap, St. Thomas lidpod, transparent wood rose, turpeth root, white day glory • Hindi: निशोथ nisoth, पनिला panila, पिठोरी pitohri • Kannada: aluthi gida, bangada balli, bilitigade, devadanti, nagadanti • Malayalam: tigade • Marathi: निसोत्तर or निशोत्तर nisottar • Sanskrit: निशोत्र nishotra, त्रिपुट triputa,त्रिवृत्त trivrutt, त्रिवृथ trivrutha • Tamil: adimbu, சரளம் caralam, சிவதை civatai, கும்பஞ்சான் kumpncan, பகன்றை paganrai • Telugu: తెగడ tegada, త్రివృత్ తెల్లతెగ trivrut tellatega • Bengali त॓वूडी tevudi • Arabic turbuth.  It is known to be a mild laxative.
     
  • Pinus roxburghii (known as chir pine) is a species of pine native to the Himalayas.
     
  • Enterococcus faecalis – formerly classified as part of the Group D Streptococcus system – is a Gram-positive, commensal bacterium inhabiting the gastrointestinal tracts of humans and other mammals. Like other species in the genus Enterococcus, E. faecalis can cause life-threatening infections in humans, especially in the nosocomial (hospital) environment, where the naturally high levels of antibiotic resistance found in E. faecalis contribute to its pathogenicity. E. faecalis has been frequently found in root canal-treated teeth in prevalence values ranging from 30% to 90% of the cases. Root canal-treated teeth are about nine times more likely to harbor E. faecalis than cases of primary infections.
     
  • Bacillus subtilis,  is a Gram-positive, catalase-positive bacterium.  Although this species is commonly found in soil, more evidence suggests B. subtilis is a normal gut commensal in humans. A 2009 study compared the density of spores found in soil (about 106 spores per gram) to that found in human feces (about 104 spores per gram). The number of spores found in the human gut is too high to be attributed solely to consumption through food contamination. Soil simply serves as a reservoir, suggesting B. subtilis inhabits the gut and should be considered as a normal gut commensal.
     
  • Micrococcus luteus is a Gram-positive, bacterium found in soil, dust, water and air, and as part of the normal flora of the mammalian skin. The bacterium also colonizes the human mouth, mucosae, oropharynx and upper respiratory tract. M. luteus is only considered a contaminant in sick patients.
     

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  • Pseudomonas aeruginosa is a common bacterium that can cause disease in animals, including humans, its versatility enables the organism to infect damaged tissues or those with reduced immunity. The symptoms of such infections are generalized inflammation and sepsis. If such colonizations occur in critical body organs, such as the lungs, the urinary tract, and kidneys, the results can be fatal.

 

Overall

My interpretation of these results is that one would have to be very very careful in the use of these plants, as they have the potential to destroy natural gut flora as well as destructive bacteria.

They are in a sense general anti-bacterial agents of more use externally than internally

A description of the experience

J Pharm Bioallied Sci. 2013 Oct;5(4):265-9. doi: 10.4103/0975-7406.120073.

Antibacterial activity of resin rich plant extracts.

Shuaib M1, Ali A, Ali M, Panda BP, Ahmad MI.  1Department of Pharmacy, Kalka Institute for Research and Advanced Studies, Meerut, Uttar Pradesh, India.

Abstract

BACKGROUND:  The in vitro antibacterial activity of resin rich methanolic extracts (RRMEs) of Commiphora myrrha, Operculina turpethum, and Pinus roxburghii.

MATERIALS AND METHODS:  Different concentration were studied by agar-well diffusion method against Gram-positive (Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus, Enterococcus faecalis) and Gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Shigella dysenteriae).

RESULTS:  Among all the bacterial strains tested, E. faecalis was most sensitive and S. typhi was resistant to C. myrrha and P. roxburghii. The extracts of O. turpethum were active against all tested strains in which B. subtilis and S. aureus were the most sensitive.

CONCLUSION:  This suggested that the antibacterial activity of RRMEs of O. turpethum was more than C. myrrha and P. roxburghii. This probably explains the potential of these plants against a number of infections caused by bacterial strains tested.

KEYWORDS:  Antibacterial drugs; Commiphora myrrha; Operculina turpethum; Pinus roxburghii; glycosidic resins; oleo-gum-resins; oleo-resins

PMID: 24302834

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Commonsteps

References