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Dr Duke's list of chemicals having anti-malarial activity

Identifier

018059

Type of Spiritual Experience

Background

A description of the experience

Dr. Duke's
Phytochemical and Ethnobotanical Databases

 

 

Chemicals with Antimalarial Activity


11-BETA-ACETOXYGEDUNIN IC50=3.11 ug/ml

ACACETIN IC50=4.2-12.6 ug/ml

AILANTHINONE IC50=0.025 uM

AILANTHONE

AJOENE 50 mg/kg

AJUGARIN-I IC50=23 uM

AKUAMMIDINE IC50=0.08-0.9 ug/ml

AKUAMMINE (1/500th chloroquine) 1 mg/kg

ALPHA-CYPERONE 5.5 ug/ml IC50=5.5 ug/ml

ALPHA-SELINENE IC50=>50 ug/ml

ALPHA-YOHIMBINE IC50=>200 uM

ANNONACIN IC50=1.3-1.5 ppm

APIOLE

ARBORININE IC50=8.5 ug/ml

ARTEMETIN (Synergic w artemisinin) IC50=26 uM

ARTEMISININ ED50=90 mg/kg orl mus ED95=1,000 mg/man/day IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day)

ASCARIDOLE 0.05-0.1 uM

ASIMICIN IC50=4 ppm

AZADIRADIONE IC50=3 ug/ml

AZADIRONE IC50=12 ug/ml

BEBEERINE

BERBERASTINE 0.14-0.36 ug/ml 50 uM

BERBERINE 0.14-0.36 ug/ml 50 uM

BETA-SELINENE IC50=>50 ug/ml

BETULINIC-ACID IC50=19-26 ug/ml

CASTICIN (Synergic w artemisinin) IC50=24 uM

CELASTROL IC50=0.181-0.254 ug/ml

CEPHAELINE IC50=0.011-0.027 uM

CHAPARRINONE IC50=0.037 ug/ml

CINCHONIDINE 150-500 mg/man/4 x day

CINCHONINE LD50=152 (ipr rat)

CIRSILINEOL IC50=36 uM

COLCHICINE 500 ug/10x/day/man

COLUMBAMINE 0.72 ug/ml

CORYNANTHEINE IC50=81 uM

CORYNANTHINE IC50=>200 uM

CURINE

CYPERENE IC50=>50 ug/ml

DAMNACANTHAL IC50=9-83 ug/ml

DIGITOLUTEIN IC50=13-83 ug/ml

DIHYDROCORYNANTHEINE IC50=66 uM

DIHYDROQUINIDINE

ELLAGIC-ACID IC50=0.5 uM

EMETINE

EUPATORIN IC50=65 uM

GEDUNIN IC50=0.3-1 uM IC50=0.7-8.5 ug/ml IC50=50 ug/ml

GENTIOPICRIN

GLAUCARUBIN

GLAUCARUBINONE ED=0.006 ug/ml

GOSSYPOL IC50=10 uM

HARMALINE

HARMINE

HOMOHARRINGTONINE

HUMULENE IC50=86 ug/ml

HYDROQUINIDINE

HYDROQUINONE

ICAJINE IC50=>80-95 uM

ISOCHONDRODENDRINE IC50=892 uM

ISOFRAXIDIN IC50=7.95 ug/ml

ISOSTRYCHNINE IC50=14->20 uM

ISOTETRANDRINE IC50=0.07 ug/ml (2 x chloroquine) IC50=100 ug/ml

JATRORRHIZINE IC50=0.42-1.61 ug/ml

LAPACHOL

LICOCHALCONE-A

LIMONIN IC50=>100 ug/ml

LUPEOL IC50=46.8 ug/ml

LYCORINE IC50=0.3-0.7 ug/ml

MAACKIAIN EC50=10 ug/ml

MELDENIN IC50=5.2 ug/ml

MYRTENAL IC50=5-50 ug/ml

MYRTENOL IC50=5-50 ug/ml

NEUROLENIN-A IC50=0.9 uM

NEUROLENIN-B IC50=0.6 uM

NIMBANDIOL IC50=50 ug/ml

NIMBIN IC50=50 ug/mL

NIMBININ IC50=0.77 ug/ml

NIMBOLIDE IC50=0.001 ug/ml IC50=1.74 ug/mL

NIMOCINOL IC50=50 ug/ml

OBAMEGINE IC50=0.51 ug/ml (1/4 x chloroquine)

OLEANOLIC-ACID IC50=70-89 ug/ml

OSTHOL IC50=25.1 ug/ml

OSTHOLE

OSTRUTHIN

OXYACANTHINE IC50=0.3 ug/ml

PALMATINE

PATCHOULENE IC50=108 uM

PHLORIZIN

PLUMBAGIN IC50=0.178-0.189 ug/ml IC50=0.3 uM

PSYCHOTRINE IC50=0.1-0.4 uM

PUNICALAGIN 2-8 ug/ml

QUERCETIN IC50=1-6.4 ug/ml

QUINICINE IC50=11.2 ug/ml

QUININE IC50=0.18 ug/ml

QUINOLINE

RUBIADIN-1-METHYL-ETHER IC50=8-83 ug/ml

RUTIN IC50=>100 ug/ml

SALANNIN IC50=50 ug/mL

SKIMMIANINE IC50=48.2 ug/ml

TRANS-PINOCARVEOL IC50=5-50 ug/ml

URSOLIC-ACID IC50=28-37 ug/ml

VOACANGINE IC50=0.3-0.5 ug/ml

VOMICINE IC50=>30 uM

The source of the experience

Dr Dukes plant database

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Concepts

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References