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Azathioprine is an immunosuppressive drug used in organ transplantation and autoimmune diseases and belongs to the chemical class of purine analogues. Synthesized originally as a cancer drug and a prodrug for mercaptopurine in 1957, it has been widely used as an immunosuppressant for more than 50 years.

The main adverse effect of azathioprine is bone marrow suppression, which can be life-threatening.   It is also listed by the International Agency for Research on Cancer as a group 1 carcinogen (carcinogenic to humans).

Azathioprine is produced by a number of manufacturers under different brand names Azasan  in the U.S., Imuran in Canada, the U.S., Australia, Ireland and the United Kingdom, Azamun in Finland, and Imurel in Scandinavia and France, among others. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

On Sep, 10, 2015: 14,262 people reported to have side effects when taking Azathioprine. Among them, 22 people (0.15%) have Hallucination.

 when sold under the brand name Imuran, Azathioprine (AZA),  is used in rheumatoid arthritis, Crohn's disease, ulcerative colitis, and in kidney transplants to prevent rejection.[sic] It is taken by mouth or injected into a vein.