Intense and recurrent déjà vu experiences related to amantadine and phenylpropanolamine in a healthy male
Type of Spiritual Experience
Phenylpropanolamine (PPA) is a sympathomimetic agent which is used as a decongestant and appetite suppressant. It is commonly used in prescription and over-the-counter cough and cold preparations
A description of the experience
J Clin Neurosci. 2001 Sep;8(5):460-2.
Intense and recurrent déjà vu experiences related to amantadine and phenylpropanolamine in a healthy male.
Taiminen T1, Jääskeläinen SK.
We report a case of a 39-year-old caucasian healthy male physician who developed intense and recurrent déjà vu experiences within 24h of initiating concomitant amantadine-phenylpropanolamine treatment against influenza.
Déjà vu experiences terminated on discontinuation of medication.
..... previous case reports have confirmed that both amantadine and phenylpropanolamine alone, and particularly in combination, can induce psychotic symptoms due to their dopaminergic activity. The authors suggest that déjà vu experiences may be provoked by increased dopamine activity in mesial temporal structures of the brain.