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Observations placeholder

Addison's disease and mood disorders

Identifier

007004

Type of Spiritual Experience

Hallucination

Number of hallucinations: 1

Background

A description of the experience

J Neuropsychiatry Clin Neurosci. 2006 Fall;18(4):450-9.  The neuropsychiatric profile of Addison's disease: revisiting a forgotten phenomenon.  Anglin RE, Rosebush PI, Mazurek MF.

One hundred fifty years since Thomas Addison's original description of the disease, it is not commonly appreciated that patients with Addison's disease may present with psychiatric symptoms. A review of the literature indicates that disturbances in mood, motivation, and behavior are associated with Addison's disease. Psychosis occurs less frequently, but can be the presenting symptom of a life-threatening adrenal crisis. Potential mechanisms for the neuropsychiatric symptoms of Addison's disease include electrophysiological, electrolyte and metabolic abnormalities, glucocorticoid deficiency, increased endorphins, and an associated Hashimoto encephalopathy. Physicians must be aware that Addison's disease may present solely with psychiatric symptoms and maintain a high index of suspicion for this potentially fatal condition.

PMID:  17135373

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Commonsteps

References