Overload

Sepsis

Category: Illness or disabilities

Type

Involuntary

Introduction and description

Nick Gentry

Sepsis is  a set of symptoms that indicate that the body is suffering from attack by one or more very dangerous pathogens. It is on the increase:

The incidence of septic shock is increasing and mortality ranges from 30% to 70%. The commonest sources of infection are lung (25%), abdomen (25%), and other sources. Septic shock occurs because of highly complex interactions between the infecting microorganism(s) and the responses of the human host. The innate immune response is rapidly followed by the more specific adaptive immune response. PMID:  18971911

Despite the fact that sepsis is increasing, hospitals seem not to have questioned either their treatment procedures or their diagnostic procedures:

Nationwide case-related hospital DRG statistics for the years 2007-2013 were used to determine the in-hospital incidence and mortality of sepsis. … The number of cases of sepsis rose by an average of 5.7% per year, from 200,535 in 2007 to 279,530 in 2013, corresponding to an increase in the adjusted in-hospital incidence from 256 to 335 cases per 100 000 persons per year. The percentage of patients with severe sepsis rose from 27% to 41%. … In 2013, 67,849 persons died of sepsis in German hospitals……… PMID:  27010950

Robert Bubel

And the problem is worldwide

To determine recent trends in rates of hospitalization, mortality, and hospital case fatality for severe sepsis in the United States….. from 1993 to 2003…… we identified 8,403,766 patients with sepsis, including 2,857,476 patients with severe sepsis, who were hospitalized in the United States from 1993 to 2003. The percentage of severe sepsis cases among all sepsis cases increased continuously from 25.6% in 1993 to 43.8% in 2003   CONCLUSIONS:  The rate of severe sepsis hospitalization almost doubled during the 11-yr period studied and is considerably greater than has been previously predicted. Mortality from severe sepsis also increased significantly. PMID:  17414736

Symptoms

There may be fever, coma, increased breathing rate, increased heart rate, even delirium, but these are simply outward signs of a very serious battle internally.  The immune system of the body is having to fight for your life and as a consequence as part of the overall battle, there may be casualties - 'friendly fire', damage to the body's own tissues and organs. 

If a virus has secreted itself in a cell, for example, the body may decide to kill that cell in order to kill the virus.

Needless to say this fight not only invokes the sympathetic nervous system, it demands a great deal of energy from reserves, the troops have to be fuelled by something, as such one should expect blood sugar levels to be high.  Thus one easily recognised symptom of sepsis is hyperglycaemia.

Interestingly, high blood glucose levels may thus be an outward sign of an internal infection, not diabetes and to treat the glucose levels one must hunt out the pathogen.

Causes

 

All the familiar causes appear in the list for the ultimate cause of sepsis  - viruses, bacteria, vaccines, fungi, parasites, radiation, heavy  metals [including dental fillings], toxins and pharmaceuticals

Treatment

The doctor MUST FIND THE CAUSE. 

The person should never be given medication until the cause is found, as if the pathogen is serious enough to cause sepsis, the wrong pharmaceuticals could kill the patient.

Remember that Sepsis is caused by an immune response to a pathogen somewhere in the body.  In other words the pathogen could be anywhere - -lungs, brain, urinary tract, kidneys, pancreas, intestines, skin, stomach, heart and so on.

The doctors should employ testing of blood cultures and lymph, testing as many pathogens as possible.  It may be possible to narrow down which pathogens by taking a history of the movements of the patient.  Medical imaging should be used to look for the possible location [s] of infection.

Until such time as the cause is found, the patient is usually given intravenous fluids to at least match in volume those lost through sweating, urinating, vomiting and diarrhoea.  None of these bodily functions should be prevented, as it is the body's way of attempting to remove the pathogen.

 

The patient must be kept clean [using warm water showers or baths and NO SOAP] and warm

Furthermore, they should be in a perfectly quiet place with no disturbance in order that they can sleep, as the body is better able to fight infection when sleeping.

Wikipedia appears to advise the following
Antibiotics are typically given as soon as possible. This is often done in an intensive care unit. If fluid replacement is not enough to maintain blood pressure, medications that raise blood pressure can be used. Mechanical ventilation and dialysis may be needed to support the function of the lungs and kidneys, respectively.  ….Some might benefit from tight control of blood sugar levels with insulin. The use of corticosteroids is controversial. Activated drotrecogin alfa, originally marketed for severe sepsis, has not been found to be helpful and was withdrawn from sale in 2011

 

If this is representative of standard medical treatment, then it probably accounts for the number of people who die from sepsis and the increase in the figures. 

If the pathogen is attacking the heart, the last thing you should do is to raise the blood pressure.  If the pathogen is not bacterial, then the last thing one should ever do is give antibiotics, as you destroy the intestinal flora – a key part of the body’s immune defences. 

The blood sugar levels are high if the body needs the glucose to fight the pathogen, by giving the body insulin you starve the very troops that are helping to fight infection. 

And giving someone an immunosuppressant that suppresses the immune system – the only defence the person has, is effectively signing their death warrant.

How it works

Most people suffering from near death experiences, out of body experiences and hallucinations do so from the underlying cause.  Thus it is not possible to say specifically how these experiences occurred without knowing what caused the sepsis.

Neverthless, the fever, that often accompanies sepsis, produces delirium and spiritual experiences; and so does being in a coma.

Related observations