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Diltiazem (INN) (/dɪlˈtaɪəzɛm/) is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It relaxes the smooth muscles in the walls of arteries, which opens (dilates) the arteries, allows blood to flow more easily, and lowers blood pressure. Additionally, it lowers blood pressure by acting on the heart itself to reduce the rate, strength, and conduction speed of each beat.

It is also used off-label as an effective preventive medication for migraine. It is a class 3 antianginal drug, and a class IV antiarrhythmic. It is a common adulterant of cocaine seized in the UK, and has been found to reduce cocaine cravings in rats, indicating it may prolong the "high" (see below).

Most common Diltiazem hydrochloride side effects from eHealthme

• Weakness - (346 reports)
• Hypotension - (324 reports)
• Nausea - (314 reports)
• Chest pain - (293 reports)
• Fatigue - (268 reports)
• Arrhythmias - (267 reports)
• Atrial fibrillation/flutter - (262 reports)
• Breathing difficulty - (262 reports)
• Fever - (246 reports)
• Dizziness - (237 reports)

On Feb, 06, 2017  6,238 people reported to have side effects when taking Diltiazem Hydrochloride. Among them, 81 people (1.3%) have Death

On Jan, 11, 2017  6,238 people reported to have side effects when taking Diltiazem Hydrochloride.  Among them, 27 people (0.43%) have Hallucination

On Jan, 29, 2017 6,238 people reported to have side effects when taking Diltiazem Hydrochloride.  Among them, 6 people (0.1%) have Hallucination, Auditory

On Jan, 28, 2017  6,238 people reported to have side effects when taking Diltiazem Hydrochloride.  Among them, 47 people (0.75%) have Hallucinogen Abuse

Most common Tiazac side effects

• Weakness - (290 reports)
• Nausea - (287 reports)
• Fatigue - (275 reports)
• Breathing difficulty - (256 reports)
• Pain - (251 reports)
• Chest pain - (239 reports)
• Dizziness - (239 reports)
• Stress and anxiety - (224 reports)
• Headache - (220 reports)
• High blood pressure - (194 reports)

On Feb, 14, 2017  3,366 people reported to have side effects when taking Tiazac.
Among them, 75 people (2.23%) have Death

On Feb, 12, 2017  3,366 people reported to have side effects when taking Tiazac.  Among them, 29 people (0.86%) have Hallucination

On Feb, 14, 2017  3,366 people reported to have side effects when taking Tiazac.  Among them, 7 people (0.21%) have Hallucination, Auditory

On Jan, 26, 2017  3,366 people reported to have side effects when taking Tiazac.  Among them, 1 person (0.03%) has Hallucinogen Abuse