Type of Spiritual Experience
A description of the experience
Calcitriol (INN), also called 1,25-dihydroxycholecalciferol or 1,25-dihydroxyvitamin D3, is the hormonally active metabolite of vitamin D with three hydroxyl groups (abbreviated 1,25-(OH)2D3 or simply 1,25(OH)2D), It was first identified by Michael F. Holick in work published in 1971. Calcitriol increases the level of calcium (Ca2+) in the blood by increasing the uptake of calcium from the gut into the blood, and possibly increasing the release of calcium into the blood from bone.
Calcitriol is prescribed for:
- Treatment of hypocalcaemia – hypoparathyroidism, osteomalacia (adults), rickets (infants, children), renal osteodystrophy, chronic kidney disease
- Treatment of osteoporosis
- Prevention of corticosteroid-induced osteoporosis
Calcitriol is also sometimes used topically in the treatment of psoriasis, however the evidence to support its efficacy is not well established. Calcitriol is also administered orally for the treatment of psoriasis and psoriatic arthritis.
The main adverse drug reaction associated with calcitriol therapy is hypercalcemia – early symptoms include: nausea, vomiting, constipation, anorexia, apathy, headache, thirst, pruritus, sweating, and/or polyuria. Compared to other vitamin D compounds in clinical use (cholecalciferol, ergocalciferol), calcitriol has a higher risk of inducing hypercalcemia
Most common Rocaltrol side effects from eHealthme
- Weakness - (359 reports)
- Fever - (276 reports)
- Nausea - (243 reports)
- Anaemia - (223 reports)
- Fatigue - (217 reports)
- Pain - (203 reports)
- High blood pressure - (182 reports)
- Breathing difficulty - (181 reports)
- Hypotension - (175 reports)
- Nausea and vomiting - (173 reports)
On Feb, 10, 2017 4,494 people reported to have side effects when taking Rocaltrol.
Among them, 91 people (2.02%) have Death
On Feb, 14, 2017 4,494 people reported to have side effects when taking Rocaltrol. Among them, 23 people (0.51%) have Hallucination
On Feb, 14, 2017 4,494 people reported to have side effects when taking Rocaltrol. Among them, 9 people (0.2%) have Hallucination, Auditory