Observations placeholder
metronidazole
Identifier
001143
Type of Spiritual Experience
Background
A description of the experience
Metronidazole is marketed under the trade name Flagyl , Nidagyl , and Mepagyl.
On Jan, 19, 2017 11 people reported to have side effects when taking Metronidazole In Plastic Container. Among them, 1 person (9.09%) has Hallucination
On Dec, 22, 2016 20,441 people reported to have side effects when taking Metronidazole. Among them, 130 people (0.64%) have Hallucinations
On Jan, 01, 201714,208 people reported to have side effects when taking Flagyl.
Among them, 130 people (0.91%) have Hallucination
It is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal. I have included it because not only may it work differently to give you a spiritual experience, but it also works differently as an antibiotic. Metronidazole is selectively absorbed by anaerobic bacteria and sensitive protozoa. Once taken up, it is non-enzymatically reduced by reacting with intermediates which then deactivate critical enzymes. As many as 150 separate enzymes are affected. In addition, the metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules.
Toxic levels of metronidazole can cause symmetrical lesions in the brain in the corpus callosum and dentate nuclei. Metronidazole toxicity is rare (though the actual incidence is not known with certainty). Patients present with nausea, vomiting, dysarthria, vertigo, and confusion. Other side effects of the metronidazole can include dry mouth, diarrhea, headache, dizziness, or peripheral neuropathy. An examination of a patient reveals that the patient is confused and has dysarthria (difficult or unclear articulation of speech that is otherwise linguistically normal), ataxia (loss of full control of bodily movements), abnormal eye movements including nystagmus and ophthalmoparesis. Magnetic resonance imaging (MRI) most often shows bilateral symmetric fluid-attenuated inversion recovery (FLAIR) hyperintense lesions of the dentate nuclei (which is one of the deep cerebellar nuclei), as well as symmetric lesions of the corpus callosum and basal ganglia. It has a subacute to acute course. Most reports have been seen in patients who receive approximately one gram a day of metronidazole for over 30 days.
In effect, what we are seeing here is the toxic levels again causing the effects, but this time the effects are being achieved by brain damage – see brain damage section for more details.
Psychotic illness following termination of pregnancy - Davidson K Clare AW - Department of Psychological Medicine, St Bartholomew's Hospital, West Smithfield, London.
A case of a psychotic illness following an induced termination of pregnancy is described; this is discussed in relation to the literature on the subject, and possible aetiological factors in the case are reviewed.
A case of psychosis occurring 13 days after 1st trimester abortion in a 17-year old primigravida without family history of mental illness of postpartum psychosis is described.
The young woman denied any ambivalence or guilt concerning abortion. The abortion itself involved repeat hospitalization for evacuation of retained products, and a course of antibiotics (metronidazole).
The illness was marked by insomnia, anorexia, labile mood, auditory hallucinations, inappropriate speech, flat affect, and withdrawal alternating with disinhibition. She was hospitalized 10 days after onset, and treated with neuroleptics (pimozide 4 mg/day). She improved rapidly, and was discharged, taking medication for a few more weeks.
After stopping medication she became pregnant, and delivered without any further psychotic symptoms.
From eHealthme Most common Metronidazole side effects:
- Pain in Metronidazole (1,024 reports)
- Fever in Metronidazole (1,000 reports)
- Diarrhea in Metronidazole (970 reports)
- Nausea in Metronidazole (883 reports)
- Stress And Anxiety in Metronidazole (812 reports)
- Weakness in Metronidazole (707 reports)
- Nausea And Vomiting in Metronidazole (701 reports)
- Hypotension in Metronidazole (641 reports)
- Breathing Difficulty in Metronidazole (622 reports)
Time on Metronidazole when people have Hallucination :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Hallucination | 96.88% | 3.12% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
On Oct, 11, 2015: 13,092 people reported to have side effects when taking Metronidazole. Among them, 261 people (1.99%) have Death.
Time on Metronidazole when people have Death :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Death | 83.33% | 7.58% | 7.58% | 0.00% | 1.52% | 0.00% | 0.00% |
Age of people who have Death when taking Metronidazole :
| 0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
| Death | 2.68% | 1.34% | 2.68% | 5.80% | 4.02% | 15.18% | 13.39% | 54.91% |