Observations placeholder

Methotrexate and Methotrexate sodium

Identifier

019521

Type of Spiritual Experience

Hallucination

Number of hallucinations: 255

Background

A description of the experience

Methotrexate (MTX) and formerly known as amethopterin, is an antimetabolite and antifolate drug.

It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions.   It acts by inhibiting the metabolism of folic acid.

Adverse effects

The most common adverse effects include: hepatotoxicity (liver damage), ulcerative stomatitis, low white blood cell count and thus predisposition to infection, nausea, abdominal pain, fatigue, fever, dizziness, acute pneumonitis, rarely pulmonary fibrosis and kidney failure Methotrexate is teratogenic (harmful to fetus) and hence not used in pregnancy (pregnancy category X).

Central nervous system reactions to methotrexate have been reported, especially when given via the intrathecal route, which include myelopathies and leucoencephalopathies. It has a variety of cutaneous side effects, particularly when administered in high doses.

Another little understood but serious possible adverse effect of methotrexate is neurological damage and memory loss. Neurotoxicity may result from the drug crossing the blood-brain barrier and damaging neurons in the cerebral cortex. Cancer patients who receive the drug often nickname these effects 'Chemo brain' or 'Chemo fog'

On Jan, 02, 2017 11,813 people reported to have side effects when taking Methotrexate Sodium.  Among them, 7 people (0.06%) have Hallucination

On Jan, 04, 2017 209,150 people reported to have side effects when taking Methotrexate.   Among them, 248 people (0.12%) have Hallucination

Time on Methotrexate when people have Hallucination  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucination 47.83% 4.35% 8.70% 4.35% 21.74% 0.00% 13.04%

Gender of people who have Hallucination when taking Methotrexate  :

  Female Male
Hallucination 62.04% 37.96%

 

 

On Dec, 13, 2015: 130,007 people reported to have side effects when taking Methotrexate. Among them, 1,361 people (1.05%) have Death.

Time on Methotrexate when people have Death  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Death 23.53% 23.53% 11.76% 13.53% 12.35% 12.35% 2.94%

Gender of people who have Death when taking Methotrexate  :

  Female Male
Death 59.45% 40.55%

Age of people who have Death when taking Methotrexate  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Death 0.41% 1.63% 4.17% 3.66% 3.05% 8.95% 17.60% 60.53%

Top conditions involved for these people  :

  1. Rheumatoid arthritis (750 people, 55.11%)
  2. Prophylaxis (86 people, 6.32%)
  3. Osteoporosis (61 people, 4.48%)
  4. Hypertension (53 people, 3.89%)
  5. Pain (44 people, 3.23%)

 

On Jan, 7, 2016: 7,196 people reported to have side effects when taking Methotrexate sodium. Among them, 79 people (1.10%) have Death.

 

 

The source of the experience

eHealthme

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Commonsteps

References