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Observations placeholder

Ehlers Danlos syndrome

Identifier

007000

Type of Spiritual Experience

Background

I have ignored the use of supplements and concentrated on the hypothesis.  Doctors always think the solution is a pill.  The rest of us realise food is better - better balanced.  You just need to eat the right [organically produced] foods.  There is the added danger with supplements that you will overdose. Pubmed has a number of papers of people who suffered from liver injury from supplements. 

Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is part of the structure of the polysaccharides chitosan and chitin, which compose the exoskeletons of crustaceans and other arthropods, as well as the cell walls of fungi and many higher organisms.

There is some evidence that foods containing glucosamine help with bone injuries.  The main [edible] food sources are:

 - Certain fungi

 - Bone marrow

Sprouted seeds may also be an option but as yet I could find no papers on this.

A description of the experience

Med Hypotheses. 2005;64(2):279-83. A novel therapeutic strategy for Ehlers-Danlos syndrome based on nutritional supplements. Mantle D1, Wilkins RM, Preedy V. Pharma Nord (UK), Telford Court, Morpeth, Northumberland NE61 2DB, UK. pharma.nord4@btconnect.com

Ehlers-Danlos syndrome is a rare disorder, comprising a group of related inherited disorders of connective tissue, resulting from underlying abnormalities in the synthesis and metabolism of collagen.

This proposal is specifically concerned with Ehlers-Danlos syndrome classic type (formerly Types I-III), which is characterized by joint hypermobility and susceptibility to injury/arthritis, skin and vascular problems (including easy bruising, bleeding, varicose veins and poor tissue healing), cardiac mitral valve prolapse, musculo-skeletal problems (myopathy, myalgia, spinal scoliosis, osteoporosis), and susceptibility to periodontitis.

No treatment is currently available for this disorder. The novel aspect of this proposal is based on:
(i) increasing scientific evidence that nutrition may be a major factor in the pathogenesis of many disorders once thought to result from defective genes alone;
(ii) the recognition that many of the symptoms associated with Ehlers-Danlos syndrome are also characteristic of nutritional deficiencies;
(iii) the synergistic action within the body of appropriate combinations of nutritional supplements in promoting normal tissue function.

We therefore hypothesize that the symptoms associated with Ehlers-Danlos syndrome may be successfully alleviated using a specific (and potentially synergistic) combination of nutritional supplements, comprising calcium, carnitine, coenzyme Q(10), glucosamine, magnesium, methyl sulphonyl methane, pycnogenol, silica, vitamin C, and vitamin K, at dosages which have previously been demonstrated to be effective against the above symptoms in other disorders.

PMID: 15607555

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Commonsteps

References