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Under the generic name algeldrate, aluminium hydroxide is used as an antacid. Brand names include Alu-Cap, Aludrox, Gaviscon or Pepsamar. It reacts with excess acid in the stomach, reducing the acidity of the stomach content, which may relieve the symptoms of ulcers, heartburn or dyspepsia. It can however cause constipation and is therefore often used with magnesium hydroxide or magnesium carbonate, which have counterbalancing laxative effects. This compound is also used to control phosphate (phosphorus) levels in the blood of people suffering from kidney failure.

Precipitated aluminium hydroxide is included as an adjuvant in some vaccines (e.g. anthrax vaccine). One of the well-known brands of aluminium hydroxide adjuvant is Alhydrogel, made by Brenntag. Since it absorbs protein well, it also functions to stabilize vaccines by preventing the proteins in the vaccine from precipitating or sticking to the walls of the container during storage. Aluminium hydroxide is sometimes mistakenly called "alum": "alum" properly refers to aluminium potassium sulfate.

Vaccine formulations containing aluminium hydroxide stimulate the immune system by inducing the release of uric acid, an immunological danger signal. This strongly attracts certain types of monocytes which differentiate into dendritic cells. The dendritic cells pick up the antigen, carry it to lymph nodes, and stimulate T cells and B cells

On Oct, 8, 2015: 574 people reported to have side effects when taking Aluminum hydroxide and magnesium trisilicate. Among them, 1 people (0.17%) has Hallucination.

On Oct, 8, 2015: 574 people reported to have side effects when taking Aluminum hydroxide and magnesium trisilicate. Among them, 19 people (3.31%) have Death.

Time on Aluminum hydroxide and magnesium trisilicate when people have Death  :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years Death100.00%0.00%0.00%0.00%0.00%0.00%0.00%