Some science behind the scenes

Immunosuppressants deaths and ADRs

Accolate and trade names

On Aug, 21, 2015: 3,260 people reported to have side effects when taking Accolate. Among them, 41 people (1.26%) have Death.

On Sep, 11, 2015: 328 people reported to have side effects when taking Zafirlukast. Among them, 3 people (0.91%) have Death

Azathioprine and trade names

On Sep, 10, 2015: 110 people reported to have side effects when taking Azasan. Among them, 3 people (2.73%) have Death

On Aug, 25, 2015: 14,262 people reported to have side effects when taking Azathioprine. Among them, 162 people (1.14%) have Death

On Sep, 10, 2015: 743 people reported to have side effects when taking Azathioprine sodium. Among them, 6 people (0.81%) have Death

On Sep, 5, 2015: 9,579 people reported to have side effects when taking Imuran. Among them, 116 people (1.21%) have Death

Betamethasone

On Sep, 11, 2015: 510 people reported to have side effects when taking Betamethasone dipropionate. Among them, 5 people (0.98%) have Death

On Aug, 27, 2015: 257 people reported to have side effects when taking Betamethasone sodium phosphate. Among them, 4 people (1.56%) have Death

On Sep, 1, 2015: 543 people reported to have side effects when taking Betamethasone valerate. Among them, 3 people (0.55%) have Death

Beclometasone and trade names [US only]

On Aug, 24, 2015: 2,336 people reported to have side effects when taking Qvar 40. Among them, 33 people (1.41%) have Death

On Sep, 11, 2015: 1,484 people reported to have side effects when taking Vanceril. Among them, 5 people (0.34%) have Death

On Sep, 11, 2015: 1,202 people reported to have side effects when taking Beconase. Among them, 5 people (0.42%) have Death

On Sep, 7, 2015: 1,343 people reported to have side effects when taking Vancenase. Among them, 11 people (0.82%) have Death

Budenoside and trade names

On Aug, 18, 2015: 5,154 people reported to have side effects when taking Budesonide. Among them, 87 people (1.69%) have Death

On Aug, 22, 2015: 20,889 people reported to have side effects when taking Symbicort. Among them, 391 people (1.87%) have Death

On Sep, 7, 2015: 13,723 people reported to have side effects when taking Pulmicort. Among them, 183 people (1.33%) have Death

On Sep, 7, 2015: 1,876 people reported to have side effects when taking Pulmicort flexhaler. Among them, 3 people (0.16%) have Death

On Sep, 7, 2015: 1,470 people reported to have side effects when taking Pulmicort respules. Among them, 13 people (0.88%) have Death

On Sep, 7, 2015: 4,582 people reported to have side effects when taking Rhinocort. Among them, 23 people (0.50%) have Death.

On Aug, 14, 2015: 2,462 people reported to have side effects when taking Entocort ec. Among them, 24 people (0.97%) have Death

Ciclosporin and Sandimmune

On Aug, 20, 2015: 5,866 people reported to have side effects when taking Sandimmune. Among them, 104 people (1.77%) have Death

Cortisol and hydrocortisone

On Aug, 28, 2015: 13,602 people reported to have side effects when taking Hydrocortisone. Among them, 352 people (2.59%) have Death

On Sep, 11, 2015: 464 people reported to have side effects when taking Hydrocortisone acetate. Among them, 7 people (1.51%) have Death

On Sep, 11, 2015: 1,027 people reported to have side effects when taking Hydrocortisone sodium succinate. Among them, 19 people (1.85%) have Death

On Sep, 11, 2015: 59 people reported to have side effects when taking Hydrocortisone valerate. Among them, 2 people (3.39%) have Death

On Sep, 11, 2015: 1,295 people reported to have side effects when taking Cortef. Among them, 19 people (1.47%) have Death

On Sep, 11, 2015: 587 people reported to have side effects when taking Cortril. Among them, 13 people (2.21%) have Death

Cortisone

On Sep, 4, 2015: 3,301 people reported to have side effects when taking Cortisone acetate. Among them, 51 people (1.54%) have Death

Dexamethasone and Decadron

On Aug, 12, 2015: 53,192 people reported to have side effects when taking Dexamethasone. Among them, 2,458 people (4.62%) have Death.

On Aug, 29, 2015: 524 people reported to have side effects when taking Dexamethasone acetate. Among them, 18 people (3.44%) have Death

On Aug, 28, 2015: 2,960 people reported to have side effects when taking Dexamethasone sodium phosphate. Among them, 68 people (2.30%) have Death.

On Aug, 13, 2015: 24,692 people reported to have side effects when taking Decadron. Among them, 957 people (3.88%) have Death

Fludrocortisone acetate and Florinef

On Sep, 11, 2015: 1,019 people reported to have side effects when taking Fludrocortisone acetate. Among them, 24 people (2.36%) have Death.

On Sep, 2, 2015: 1,823 people reported to have side effects when taking Florinef. Among them, 32 people (1.76%) have Death

Fluticasone and Flonase etc

On Sep, 11, 2015: 39,318 people reported to have side effects when taking Advair diskus 100/50. Among them, 960 people (2.44%) have Death.

On Aug, 26, 2015: 1,935 people reported to have side effects when taking Advair diskus 250/50. Among them, 11 people (0.57%) have Death

On Aug, 26, 2015: 328 people reported to have side effects when taking Advair diskus 500/50. Among them, 4 people (1.22%) have Death.

On Aug, 29, 2015: 6,631 people reported to have side effects when taking Advair hfa. Among them, 305 people (4.60%) have Death.

On Sep, 7, 2015: 10,085 people reported to have side effects when taking Fluticasone propionate. Among them, 116 people (1.15%) have Death

On Sep, 11, 2015: 16,919 people reported to have side effects when taking Flonase. Among them, 237 people (1.40%) have Death

Veramyst

On Aug, 26, 2015: 1,763 people reported to have side effects when taking Veramyst. Among them, 11 people (0.62%) have Death

Triamcinolone and trade names

On Sep, 11, 2015: 2,968 people reported to have side effects when taking Triamcinolone. Among them, 81 people (2.73%) have Death

On Aug, 26, 2015: 2,280 people reported to have side effects when taking Triamcinolone acetonide. Among them, 33 people (1.45%) have Death

On Sep, 11, 2015: 168 people reported to have side effects when taking Aristocort. Among them, 7 people (4.17%) have Death

On Aug, 28, 2015: 3,884 people reported to have side effects when taking Nasacort. Among them, 44 people (1.13%) have Death

On Sep, 7, 2015: 784 people reported to have side effects when taking Nasacort aq. Among them, 4 people (0.51%) have Death

On Sep, 11, 2015: 414 people reported to have side effects when taking Kenacort. Among them, 3 people (0.72%) have Death

On Aug, 19, 2015: 3,399 people reported to have side effects when taking Azmacort. Among them, 47 people (1.38%) have Death

Prednisolone

On Sep, 4, 2015: 64,621 people reported to have side effects when taking Prednisolone. Among them, 1,032 people (1.60%) have Death

On Sep, 1, 2015: 1,360 people reported to have side effects when taking Prednisolone acetate. Among them, 16 people (1.18%) have Death

On Sep, 11, 2015: 451 people reported to have side effects when taking Prednisolone sodium phosphate. Among them, 2 people (0.44%) have Death

On Sep, 11, 2015: 5,147 people reported to have side effects when taking Methylprednisolone. Among them, 48 people (0.93%) have Death

On Sep, 11, 2015: 1,038 people reported to have side effects when taking Methylprednisolone acetate. Among them, 21 people (2.02%) have Death

On Sep, 11, 2015: 2,355 people reported to have side effects when taking Methylprednisolone sodium succinate. Among them, 18 people (0.76%) have Death

On Sep, 1, 2015: 9,212 people reported to have side effects when taking Medrol. Among them, 177 people (1.92%) have Death

On Sep, 3, 2015: 14,755 people reported to have side effects when taking Solu-medrol. Among them, 359 people (2.43%) have Death

Prednisone

On Sep, 7, 2015: 146,879 people reported to have side effects when taking Prednisone. Among them, 3,016 people (2.05%) have Death.

Tacrolimus

On Aug, 29, 2015: 13,508 people reported to have side effects when taking Tacrolimus. Among them, 825 people (6.11%) have Death

On Aug, 18, 2015: 19,883 people reported to have side effects when taking Prograf. Among them, 893 people (4.49%) have Death

On Aug, 12, 2015: 1,738 people reported to have side effects when taking Protopic. Among them, 12 people (0.69%) have Death.

Sirolimus  and trade names

On Sep, 11, 2015: 1,895 people reported to have side effects when taking Sirolimus. Among them, 53 people (2.80%) have Death

On Sep, 11, 2015: 7,410 people reported to have side effects when taking Rapamune. Among them, 186 people (2.51%) have Death

Infliximab and trade names

On Aug, 24, 2015: 85,116 people reported to have side effects when taking Remicade. Among them, 1,500 people (1.76%) have Death.

Rituximab and trade names

On Aug, 15, 2015: 10,206 people reported to have side effects when taking Rituxan. Among them, 392 people (3.84%) have Death

Singulair and  Montelukast

On Sep, 11, 2015: 3,090 people reported to have side effects when taking Montelukast sodium. Among them, 46 people (1.49%) have Death

On Sep, 3, 2015: 41,274 people reported to have side effects when taking Singulair. Among them, 447 people (1.08%) have Death

Paclitaxel 

On Aug, 24, 2015: 21,494 people reported to have side effects when taking Taxol. Among them, 662 people (3.08%) have Death

On Sep, 11, 2015: 16,475 people reported to have side effects when taking Paclitaxel. Among them, 462 people (2.80%) have Death

Thalomid (Thalidomide)

On Aug, 18, 2015: 26,632 people reported to have side effects when taking Thalomid. Among them, 8,852 people (33.24%) have Death.

Lenalidomide marketed as Revlimid

On Sep, 11, 2015: 42,910 people reported to have side effects when taking Revlimid. Among them, 7,390 people (17.22%) have Death

Humira

On Aug, 24, 2015: 136,050 people reported to have side effects when taking Humira. Among them, 1,149 people (0.84%) have Death

Enbrel

On Sep, 3, 2015: 175,004 people reported to have side effects when taking Enbrel. Among them, 950 people (0.54%) have Death

Everolimus and trade names

On Sep, 11, 2015: 128 people reported to have side effects when taking Zortress. Among them, 2 people (1.56%) have Death

On Aug, 30, 2015: 6,446 people reported to have side effects when taking Afinitor. Among them, 772 people (11.98%) have Death

Zileuton and Zyflo

On Sep, 11, 2015: 503 people reported to have side effects when taking Zyflo. Among them, 6 people (1.19%) have Death

On Sep, 11, 2015: 80 people reported to have side effects when taking Zyflo cr. Among them, 3 people (3.75%) have Death

Elidel

On Sep, 2, 2015: 2,609 people reported to have side effects when taking Elidel. Among them, 15 people (0.57%) have Death

Leflunomide and Arava

On Aug, 26, 2015: 16,222 people reported to have side effects when taking Arava. Among them, 193 people (1.19%) have Death.

On Sep, 7, 2015: 8,323 people reported to have side effects when taking Leflunomide. Among them, 112 people (1.35%) have Death

Mycophenolic acid, Myfortic and CellCept

On Sep, 12, 2015: 1,267 people reported to have side effects when taking Mycophenolic acid. Among them, 18 people (1.42%) have Death

On Sep, 1, 2015: 2,871 people reported to have side effects when taking Myfortic. Among them, 106 people (3.69%) have Death

On Aug, 21, 2015: 15,537 people reported to have side effects when taking Cellcept. Among them, 632 people (4.07%) have Death

Methotrexate and Trexall

On Sep, 12, 2015: 129,965 people reported to have side effects when taking Methotrexate. Among them, 1,361 people (1.05%) have Death.

On Sep, 12, 2015: 256 people reported to have side effects when taking Methotrexate lpf. Among them, 1 people (0.39%) has Death

On Sep, 12, 2015: 7,196 people reported to have side effects when taking Methotrexate sodium. Among them, 79 people (1.10%) have Death

Anakinra and Kineret

On Sep, 12, 2015: 2,008 people reported to have side effects when taking Kineret. Among them, 21 people (1.05%) have Death

Temsirolimus and Torisel

On Sep, 10, 2015: 2,078 people reported to have side effects when taking Torisel. Among them, 95 people (4.57%) have Death

Eculizumab and Soliris

On Aug, 18, 2015: 7,736 people reported to have side effects when taking Soliris. Among them, 213 people (2.75%) have Death

Certolizumab pegol and Cimzia

On Sep, 7, 2015: 12,969 people reported to have side effects when taking Cimzia. Among them, 79 people (0.61%) have Death

Golimumab and Simponi

On Sep, 10, 2015: 2,772 people reported to have side effects when taking Simponi. Among them, 29 people (1.05%) have Death

Omalizumab and Xolair

On Aug, 31, 2015: 11,499 people reported to have side effects when taking Xolair. Among them, 347 people (3.02%) have Death.

Ustekinumab trade names Stelara, Centocor

On Sep, 12, 2015: 3,771 people reported to have side effects when taking Stelara. Among them, 54 people (1.43%) have Death.

Orthoclone okt3 [Muromonab-CD3]

On Sep, 12, 2015: 491 people reported to have side effects when taking Orthoclone okt3. Among them, 5 people (1.02%) have Death

Efalizumab Brand Name Raptiva

On Sep, 12, 2015: 3,326 people reported to have side effects when taking Raptiva. Among them, 32 people (0.96%) have Death

Belimubab and Benlysta

On Sep, 7, 2015: 716 people reported to have side effects when taking Benlysta. Among them, 6 people (0.84%) have Death.

Ipilimumab and Yervoy

On Aug, 22, 2015: 1,494 people reported to have side effects when taking Yervoy. Among them, 252 people (16.87%) have Death

Natalizumab and Tysabri

On Aug, 16, 2015: 97,552 people reported to have side effects when taking Tysabri. Among them, 731 people (0.75%) have Death.

Tocilizumab or atlizumab trade names Actemra and RoActemra

On Sep, 3, 2015: 4,439 people reported to have side effects when taking Actemra. Among them, 186 people (4.19%) have Death

Belatacept (trade name Nulojix)

On Sep, 12, 2015: 65 people reported to have side effects when taking Nulojix. Among them, 3 people (4.62%) have Death.

Aflibercept, Eylea, and Zaltrap

On Sep, 3, 2015: 168 people reported to have side effects when taking Eylea. Among them, 4 people (2.38%) have Death.

 

Total deaths as of Early September 2015 for this class of drugs = 41,373

[Total anti-histamine deaths = 3,043]

ADR REPORTS    1,465,290

Total people reporting anti-histamine side effects = 190,458