Some science behind the scenes



Chronic inflammatory demyelinating polyneuropathy (CIDP) is a disorder of the peripheral nervous system. The disorder is sometimes called chronic relapsing polyneuropathy (CRP) or chronic inflammatory demyelinating polyradiculoneuropathy (because it involves the nerve roots).  CIDP is closely related to Guillain-Barré syndrome and it is considered the chronic counterpart of that acute disease. Its symptoms are also similar to progressive inflammatory neuropathy. An asymmetrical variant of CIDP is known as Lewis-Sumner syndrome.

The pathologic hallmark of the disease is loss of the myelin sheath (the fatty covering that insulates and protects nerve fibers) of the peripheral nerves.

CIDP is under-recognized and under-treated due to its heterogeneous presentation (both clinical and electrophysiological) and the limitations of clinical, serologic, and electrophysiologic diagnostic criteria. Despite these limitations, early diagnosis and treatment is important in preventing irreversible axonal loss and improving functional recovery.”

There are multiple causes, however, this LINK takes you to the eHealthme web site which lists the pharmaceuticals that are known to cause Peripheral neuropathy.  The list is not anecdotal it was compiled from recognised Adverse Drug Reaction reports submitted to the FDA.

CIDP  - its causes and the observations associated with it are treated in the more general section Nervous system diseases.