Some science behind the scenes



Bickerstaff's brainstem encephalitis (BBE) - is characterized by acute onset of ophthalmoplegia, ataxia, disturbance of consciousness, hyperreflexia or Babinski's sign. The course of the disease can be monophasic or remitting-relapsing.

Large, irregular hyperintense lesions located mainly in the brainstem, especially in the pons, midbrain and medulla, are described in the literature.

Despite severe initial presentation, BBE usually has a good prognosis. Magnetic resonance imaging plays a critical role in the diagnosis of BBE.

A considerable number of BBE patients have associated axonal Guillain–Barré syndrome [GBS] , indicative that the two disorders are closely related and form a continuous spectrum.

GBS and BBE   - their causes and the observations associated with them are treated in the more general section Nervous system diseases.



There is also a section on BBE on the site if you follow this link.