Preliminary investigation on the phytochemistry and antimicrobial activity of Senna alata L. flower
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Proteus vulgaris is a rod-shaped, nitrate-reducing, indole+ and catalase-positive, hydrogen sulfide-producing, Gram-negative bacterium that inhabits the intestinal tracts of humans and animals. It can be found in soil, water, and fecal matter. It is grouped with the Enterobacteriaceae and is an opportunistic pathogen of humans. It is known to cause wound infections and other species of its genera are known to cause urinary tract infections.
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Pak J Biol Sci. 2007 Mar 1;10(5):806-9.
Preliminary investigation on the phytochemistry and antimicrobial activity of Senna alata L. flower.
Idu M1, Omonigho SE, Igeleke CL.
- 1Department of Botany, University of Benin, PMB 1154, Benin City, Nigeria.
Preliminary studies on the phytochemistry and extracts of water, methanol, chloroform and petroleum ether, of Senna alata flowers were examined for antimicrobial properties.
Extracts tested at a final concentration of 500 microg mL(-1) produced in vitro antimicrobial activities in assays against clinical isolates of
- Staphylococus aureus,
- Candida albicans,
- Escherichia coli,
- Proteus vulgaris,
- Pseudomonans aureginosa and
- Bacillus subtilis.
The zones of inhibitions produced by the extracts in agar diffusion assay against the test micro organisms ranged from 4 to 10 mm while the gentamycin antibiotic control, produced zones that measured 5 mm. Preliminary phytochemical analysis of the plant extracts showed the presence of phenols, tannins, anthraquinoes, saponins, flavonoids.
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Bladder and urinary tract disease
Pseudomonas aeruginosa infection