Observations placeholder
Hallucinations and hypoglycaemia from anti-fungal
Identifier
013001
Type of Spiritual Experience
Number of hallucinations: 3
Background
A description of the experience
Clin Infect Dis. 2004 Oct 15;39(8):1241-4. Epub 2004 Sep 23.
Adverse reactions to voriconazole.
Boyd AE1, Modi S, Howard SJ, Moore CB, Keevil BG, Denning DW. 1Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Manchester, United Kingdom.
Voriconazole is a new antifungal agent effective in the treatment of invasive aspergillosis. Interpatient variation in plasma concentrations is considerable--more than 100-fold. We describe 3 patients with diverse manifestations of toxicity (e.g., hallucinations, hypoglycemia, electrolyte disturbance, and pneumonitis) possibly attributable to high voriconazole concentrations. Measurement of plasma concentrations could be helpful in optimizing voriconazole dosages.
PMID: 15486850