Observations placeholder
Children with unexplained seizures
Identifier
003449
Type of Spiritual Experience
Background
from a paper on PubMed
Note: In cell biology, microsomes are vesicle-like artifacts re-formed from pieces of the endoplasmic reticulum (ER) when eukaryotic cells are broken-up in the laboratory. It should be clear that, microsomes are not ordinarily present in living cells, so the fact that they are, indicates something is attacking them
A description of the experience
Unexplained seizures, confusion or hallucinations: think Hashimoto encephalopathy - Alink J, de Vries TW; Department of Pediatrics, Medical Centre Leeuwarden, Leeuwarden, The Netherlands.
AIM: Hashimoto encephalopathy (HE) is a serious but treatable condition that is probably underdiagnosed. We summarize and review all published cases to delineate the disease and to alert paediatricians so that they recognize the disease in children.
METHODS: We searched three data sources, PubMed, Cochrane and Embase, to find the articles on the subject.
RESULTS: Twenty-five children (85.8% girls) were reported being diagnosed with HE. The median age was 14 years (range 9-18 years). The most frequent clinical symptoms were seizures (80%), confusion (52%), headache (40%), hallucinations (32%) and ataxia (36%). Antimicrosomal antibodies were demonstrated in all patients, other diagnostic methods were not specific. Treatment with steroids was effective with 55% of patients showing complete recovery.
CONCLUSION: We recommend measuring antimicrosomal antibodies in all children with unexplained seizures, hallucinations or confusion and, if positive, initiating treatment with prednisolone.
The source of the experience
PubMedConcepts, symbols and science items
Concepts
Symbols
Science Items
Activities and commonsteps
Activities
Overloads
EncephalitisHashimoto encephalopathy
Thyroid disease
Suppressions
Being a childCommonsteps
References
PubMed