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Capparis spinosa L. (Caper) fruit extract in treatment of type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial
Identifier
022056
Type of Spiritual Experience
Background
The berry - and although an extract was used for the research for convenience, a person would simply eat the berry
A description of the experience
Complement Ther Med. 2013 Oct;21(5):447-52. doi: 10.1016/j.ctim.2013.07.003. Epub 2013 Aug 7. Capparis spinosa L. (Caper) fruit extract in treatment of type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Huseini HF1, Hasani-Rnjbar S, Nayebi N, Heshmat R, Sigaroodi FK, Ahvazi M, Alaei BA, Kianbakht S. 1Pharmacology and Applied Medicine Department of Medicinal Plants research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran.
OBJECTIVES:
Capparis spinosa L. (Caper) fruit is traditionally used as an anti-hyperglycemic food by Iranian diabetic patients. But yet, no controlled human study has determined its efficacy in treatment of hyperglycemia in type 2 diabetic patients.
DESIGN:
The present study was undertaken to explore the possible anti-hyperglycemic effects of the caper fruit extract in type 2 diabetic patients. A randomized clinical trial was conducted in 54 type 2 diabetic patients. Two groups 28 and 26 patients on standard anti-diabetic therapy, received 400mg caper fruit extract and placebo capsules three times a day respectively for two months.
MAIN OUTCOME MEASURES:
The patients fasting blood glucose, glycosylated hemoglobin, lipids levels, liver and renal function tests were determined at baseline and endpoint.
RESULTS:
Results showed significant decrease in fasting blood glucose levels (p=0.037) and glycosylated hemoglobin (p=0.043) in caper treated patients compared to control group at the end of the study. Triglyceride level also decreased significantly (p=0.29) in caper treated group at the end of the study compared to baseline. No liver, kidney and other side effects were observed in these two groups.
CONCLUSIONS:
Caper fruit extract may be a safe anti-hyperglycemic and anti-hypertriglyceridemic agent for type 2 diabetic patients.
PMID: 24050578