Bitter orange and hordenine
Type of Spiritual Experience
A description of the experience
Mass spectrometric determination of the predominant adrenergic protoalkaloids in bitter orange (Citrus aurantium) - Nelson BC, Putzbach K, Sharpless KE, Sander LC; Analytical Chemistry Division, Stop 8392, National Institute of Standards and Technology, Gaithersburg, Maryland, USA.
The predominant adrenergic protoalkaloid found in the peel and fruit of bitter orange, Citrus aurantium, is synephrine. Synephrine is reputed to have thermogenic properties and is used as a dietary supplement to enhance energy and promote weight loss.
However, there exists some concern that the consumption of dietary supplements containing synephrine or similar protoalkaloids may contribute to adverse cardiovascular events.
This study developed and validated a positive-ion mode liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the quantitative determination of the major (synephrine) and minor (tyramine, N-methyltyramine, octopamine, and hordenine) adrenergic protoalkaloids in a suite of National Institute of Standards and Technology (NIST) bitter orange Standard Reference Materials (SRMs): SRM 3258 Bitter Orange Fruit, SRM 3259 Bitter Orange Extract, and SRM 3260 Bitter Orange Solid Oral Dosage Form.
The source of the experiencePubMed
Concepts, symbols and science items
Activities and commonsteps
OverloadsAdrenaline and its ligands
Amphetamines and stimulants