Observations placeholder

Arthritis, bone marrow and mushrooms

Identifier

005667

Type of Spiritual Experience

Background

 

Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is part of the structure of the polysaccharides chitosan and chitin, which compose the exoskeletons of crustaceans and other arthropods, as well as the cell walls of fungi and many higher organisms.

In some cases, where the arthritis is caused by degeneration of joints – wear and tear – there is some evidence that foods containing glucosamine help. There are such things as glucosamine dietary supplements – these are produced commercially by the hydrolysis of crustacean exoskeletons or, less commonly by fermentation of a grain such as corn or wheat, but there is little point in buying dietary supplements when you can find it in foods. There is the added danger with supplements that you will overdose. The main [edible] food sources are:

 - Certain fungi

 - Bone marrow

Sprouted seeds may also be an option but as yet I could find no papers on this.

I have added the rheumatoid arthritis category as the treatments may be similar depending on the cause of the arthritis

A description of the experience

 

Rheumatol Int. 2012 Oct;32(10):2959-67. Epub 2012 Mar 30. Role of glucosamine in the treatment for osteoarthritis. Reginster JY, Neuprez A, Lecart MP, Sarlet N, Bruyere O. Department of Public Health Sciences, CHU Sart Tilman, University of Liège, Liège, Belgium. jyreginster@ulg.ac.be

Over the last 20 years, several studies have investigated the ability of glucosamine sulfate to improve the symptoms (pain and function) and to delay the structural progression of osteoarthritis. There is now a large, convergent body of evidence that glucosamine sulfate, given at a daily oral dose of 1,500 mg, is able to significantly reduce the symptoms of osteoarthritis in the lower limbs. This dose of glucosamine sulfate has also been shown, in two independent studies, to prevent the joint space narrowing observed at the femorotibial compartment in patients with mild-to-moderate knee osteoarthritis. This effect also translated into a 50 % reduction in the incidence of osteoarthritis-related surgery of the lower limbs during a 5-year period following the withdrawal of the treatment. Some discrepancies have been described between the results of studies performed with a patent-protected formulation of glucosamine sulfate distributed as a drug and those having used glucosamine preparations purchased from global suppliers, packaged, and sold over-the-counter as nutritional supplements.

PMID: 22461188

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Osteoarthritis
Rheumatoid arthritis

Suppressions

Bone marrow
Mushrooms

Commonsteps

References