Antimycobacterial crude plant extracts from South, Central, and North America
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Phytomedicine. 1998 Apr;5(2):137-45. doi: 10.1016/S0944-7113(98)80011-1.
Antimycobacterial crude plant extracts from South, Central, and North America.
Cantrell CL1, Fischer NH, Urbatsch L, McGuire MS, Franzblau SG.
- 1Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana, U.S.A.
Two-hundred and thirty crude organic extracts from 118 plant species distributed among 10 families were evaluated for anti-mycobacterial activity.
Activity was determined against Mycobacterium tuberculosis H(37)Rv and Mycobacterium avium using the BACTEC 460 radiorespirometric assay. At 100 μg/ml, twenty-four and ten of the extracts caused more than 95% inhibition of growth of M. tuberculosis and M. avium, respectively.
The most active plant species (100% inhibition) were Borrichia frutescens, Solidago arguta, and Inula helenium against M. tuberculosis, Euthamia leptocephala against M. avium, and Erigeron strigosus and Magnolia acuminata against both mycobacteria.
Copyright © 1998 Gustav Fischer Verlag. Published by Elsevier GmbH.. All rights reserved.
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