Observations placeholder

Antimalarial use of volatile oil from leaves of Virola surinamensis (Rol.) Warb. by Waiãpi Amazon Indians

Identifier

018282

Type of Spiritual Experience

Background

A description of the experience

J Ethnopharmacol. 1999 Nov 30;67(3):313-9.

Antimalarial use of volatile oil from leaves of Virola surinamensis (Rol.) Warb. by Waiãpi Amazon Indians.

Lopes NP1, Kato MJ, Andrade EH, Maia JG, Yoshida M, Planchart AR, Katzin AM.

Abstract

The Amazon Indians Waiãpi living in the West of Amapá State of Brazil, treat malaria with an inhalation of vapor obtained from leaves of Viola surinamensis. The essential oil obtained from adult and plantlet leaves was analyzed by GC/MS and 11 monoterpenes, 11 sesquiterpenes and three phenylpropanoids were identified. Plantlet essential oil caused 100% of growth inhibition after 48 h in the development of the young trophozoite to schizont stage and the sesquiterpene nerolidol (100 microg/ml) was identified as one of the active constituents (100% of growth inhibition was obtained). In addition, examination of [U14C]-glucose incorporation showed that activity of nerolidol is related to the inhibition of glycoprotein biosynthesis.

PMID:  10617066

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Monoterpene

Activities and commonsteps

Activities

Overloads

Malaria
Malaria treatments and prevention

Suppressions

Ucuuba

Commonsteps

References