Observations placeholder
Quinacrine, giardiasis and hallucinations
Identifier
006115
Type of Spiritual Experience
Background
Mepacrine also known as quinacrine or under the trade name Atabrine is used as an antiprotozoal, antirheumatic and an intrapleural sclerosing agent. Antiprotozoal use include targeting giardiasis, where mepacrine is used as a primary agent for patients with metronidazole-resistant giardiasis and patients who should not receive or can not tolerate metronidazole
A description of the experience
Hum Psychopharmacol. 2002 Oct;17(7):357-9. Quinacrine-induced psychiatric disturbances in a child with common variable immunodeficiency and chronic giardiasis. Genel F, Erermis S, Aksu G, Ozturk C, Kutukculer N. Department of Pediatrics, Ege University, The Medical School, Izmir, Turkey. ferahgen@yahoo.com
Psychiatric disorders due to quinacrine for antiparasitic therapy represent an infrequent, but serious, complication. The remarkable course of a 12-year-old boy with common variable immunodeficiency who developed severe psychiatric reactions following quinacrine therapy for his resistant chronic giardiasis is presented. The broad clinical spectrum of quinacrine-associated neuropsychiatric disturbances has been emphasized for the clinicians.
Copyright 2002 John Wiley & Sons, Ltd.
PMID: 12415556