Type of Spiritual Experience
A description of the experience
Prazosin, trade names Minipress, Vasoflex, Lentopres and Hypovase, is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder. It is an alpha-adrenergic blocker that is specific for the alpha-1 receptors. These receptors are found on vascular smooth muscle, where they are responsible for the vasoconstrictive action of norepinephrine. They are also found throughout the central nervous system.
In addition to its alpha-blocking activity, prazosin is an antagonist of the MT3 receptor (which is not present in humans), with selectivity for this receptor over the MT1 and MT2 receptors
Side effects of prazosin include orthostatic hypotension, syncope, and nasal congestion. The orthostatic hypotension and syncope are associated with the body's poor ability to control blood pressure without active alpha-adrenergic receptors. Patients on prazosin should be told not to stand up too quickly, since their poor baroreflex may cause them to faint if their blood pressure is not adequately maintained during standing. The nasal congestion is due to dilation of vessels in the nasal mucosa.
One phenomenon associated with prazosin is known as the "first dose response", in which the side effects of the drug, especially orthostatic hypotension and fainting, are especially pronounced in the first dose.
One very rare side effect of prazosin is priapism
Another possible side effect is dreaming while awake or hallucinations of wakefulness while falling asleep on the medication (see oneirophrenia).
On Jan, 7, 2016: 1,229 people reported to have side effects when taking Minipress. Among them, 4 people (0.24%) have Hallucination.
On Dec, 27, 2015: 1,229 people reported to have side effects when taking Minipress. Among them, 11 people (0.90%) have Death.
On Jan, 7, 2016: 198 people reported to have side effects when taking Minipress xl. Among them, 4 people (2.02%) have Death.
The source of the experienceeHealthme
Concepts, symbols and science items
Activities and commonsteps
OverloadsAdrenaline and its ligands
Post traumatic stress disorder (PTSD)