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Loxapine is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. Trade names for loxapine taken by mouth include Loxapac and Loxitane; the inhalable form is approved as Adasuve. The drug is a member of the dibenzoxazepine class and structurally related to clozapine (which belongs to the chemically akin class of dibenzodiazepines). Several researchers have argued that loxapine may behave as an atypical antipsychotic

Common side effects of loxapine (≥1% incidence) when inhaled include

• Taste sense altered (14%)
• Sedated (12%)
• Pharyngitis (3%)

Common side effects of orally-administered loxapine include

• Constipation
• Dry mouth
• Akathisia
• Dizziness
• Intense Sleeping (Highest Percentage)
• Blurred Speech
• Extrapyramidal disease (dose-dependent. At lower dosages its propensity for causing extrapyramidal side effects appears to be similar to that of atypical antipsychotics[9]
• Blurred vision
• Urinary retention
• Somnolence (which appears to be moderate in severity compared to other antipsychotic drugs
• Dyspnoea
• Nasal congestion

Rare side effects include]

• Paralytic ileus
• Agranulocytosis
• Leukopenia
• Thrombocytopenia
• Hepatocellular liver damage
• Neuroleptic malignant syndrome
• Seizure

On Jan, 6, 2016: 311 people reported to have side effects when taking Loxitane. Among them, 4 people (1.29%) have Hallucination.

On Dec, 31, 2015: 311 people reported to have side effects when taking Loxitane. Among them, 6 people (1.93%) have Death.