Does heaven exist? With well over 100,000 plus recorded and described spiritual experiences collected over 15 years, to base the answer on, science can now categorically say yes. Furthermore, you can see the evidence for free on the website allaboutheaven.org.

Available on Amazon
also on all local Amazon sites, just change .com for the local version (.co.uk, .jp, .nl, .de, .fr etc.)


This book, which covers Visions and hallucinations, explains what causes them and summarises how many hallucinations have been caused by each event or activity. It also provides specific help with questions people have asked us, such as ‘Is my medication giving me hallucinations?’.

Available on Amazon
also on all local Amazon sites, just change .com for the local version (.co.uk, .jp, .nl, .de, .fr etc.)

Observations placeholder

Is low dose of estrogen beneficial for prevention of glaucoma?



Type of Spiritual Experience


A description of the experience

Med Hypotheses. 2012 Sep;79(3):377-80. doi: 10.1016/j.mehy.2012.05.041. Epub 2012 Jun 22.

Is low dose of estrogen beneficial for prevention of glaucoma?

Wei X1, Cai SP, Zhang X, Li X, Chen X, Liu X.

  • 1Ophthalmic Laboratories and Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, PR China.


Glaucoma, as characterized by accelerated retinal ganglion cell (RGC) death and cupping of optic nerve head (ONH), is one of the leading causes of blindness worldwide. Elevated intraocular pressure (IOP) is generally considered as a major risk factor in the pathogenesis of glaucoma.

Previous studies showed that glaucoma caused decrease in collagen and elastin density in several ocular tissues, such as lamina cribrosa, peripapillary sclera and cornea, and resulted in reduced elasticity and compliance of these tissues.

It is known that estrogen has protective effects against glaucoma, yet the underlying mechanism still remains obscure.

Prior researches have provided evidences showing that the estrogen receptors (ERs) express in a variety of the ocular tissues. Estrogen activates the synthesis of collagen fiber and improves the compliance of these tissues.

This leads to a reasonable postulation that increased estrogen may result in a higher content of the collagen fibers and enhanced flexibility of the whole eye, which would therefore decrease IOP. Particularly, the increase in the amounts of collagen fibers at lamina cribrosa improves its compliance, which in turn relieves its compression on RGC axons. Therefore, even at the same IOP level, the softening of cribriform foramina yields a more flexible environment for the RGCs to survive.

We therefore hypothesize that estrogen at proper dosage can be considered as a potential therapy for glaucoma since it is able to prevent the eye from glaucomatous damage and lower IOP, especially for those menopausal women with glaucoma.

Copyright © 2012 Elsevier Ltd. All rights reserved.

PMID:  22727818

The source of the experience


Concepts, symbols and science items



Science Items

Activities and commonsteps