In Vitro Antiviral Activity of a New Isoflavonic Glycoside From Ulex Europaeus
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Planta Med 1990 Feb;56(1):59-62.
"In Vitro" Antiviral Activity of a New Isoflavonic Glycoside From Ulex Europaeus
D J De Rodriguez 1 , J Chulia, C M Simões, M Amoros, A M Mariotte, L Girre
Extracts from Ulex europaeus L. (Fabaceae) were tested for antiviral activity against HSV-1 and poliovirus. It was found that the n-butanolic extract significantly inhibited the replication of these viruses, as shown by inhibition of cytophathic effects and reduction of plaques; the extract has neither a prophylactic nor a virucidal activity. From this extract has been isolated and identified by chromatographic, chemical, and spectroscopic methods, the 5-O-methylgenistein 7-O-beta D-glucopyranoside. This isoflavonic glycoside has not been previously described and it is responsible at least partially for the antiviral activity.
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