Identification of α-cobratoxin in equine plasma by LC-MS, MS for doping control.
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Anal Chem. 2013 May 21;85(10):5219-25. doi: 10.1021/ac4006342. Epub 2013 Apr 30. Identification of α-cobratoxin in equine plasma by LC-MS/MS for doping control. Bailly-Chouriberry L, Cormant F, Garcia P, Kind A, Popot MA, Bonnaire Y. Laboratoire des Courses Hippiques (LCH), Verrières le Buisson, France. email@example.com
Cobra venom (Naja kaouthia) contains a toxin called α-cobratoxin (α-Cbtx). This toxin is a natural protein containing 71 amino acids (MW 7821 Da) with a reported analgesic potency greater than morphine. In 2007, in USA, this substance was found in the barns of a thoroughbred trainer and since then till date, the lack of a detection of this molecule has remained a recurring problem for the horseracing industry worldwide. ………. [rest omitted as it relates to horses]