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Observations placeholder

Dr Duke's list of Chemicals and their Biological Activities in: Liquidambar orientalis MILLER (Hamamelidaceae) -- Oriental Storax, Oriental Styrax



Type of Spiritual Experience


A description of the experience

Chemicals and their Biological Activities in: Liquidambar orientalis MILLER (Hamamelidaceae) -- Oriental Storax, Oriental Styrax


3-EPIOLEANOLIC-ACID Resin, Exudate, Sap: DUKE1992A

No activity reported.

ALPHA-SITOSTEROL Resin, Exudate, Sap: DUKE1992A

No activity reported.

ALPHA-STORESIN Resin, Exudate, Sap: DUKE1992A

No activity reported.

BENZYL-ALCOHOL Resin, Exudate, Sap: DUKE1992A

Allergenic M29 ; Anesthetic MAR ; Antiodontalgic MAR ; Antipruritic DUKE1992B ; Antiseptic M29 ; FLavor Fema 200-1,200 ARC ; Fungicide X16719518 ; Pesticide DUKE1992B ; Sedative JA6(4):40

BENZYL-CINNAMATE Resin, Exudate, Sap: DUKE1992A

Allergenic M&R416 ; FLavor FEMA 1-125 ARC ; Irritant ZEB ; Perfumery DUKE1992B

BETA-SITOSTEROL Resin, Exudate, Sap: DUKE1992A

Androgenic DUKE1992B ; Angiogenic X11988857 ; Anorexic MAR ; Antiadenomic M11 ; Antiandrogenic JE28:221 ; Antibacterial QJC28:155 ; Anticancer (Breast) PS131:95 ; Anticancer (Cervix) PJB1(2):287 ; Anticancer (Lung) PJB1(2):287 ; Antiedemic IC54=320 mg/kg orl DFN:160 ; Antiestrogenic JE28:221 ; Antifeedant 382 ; Antifertility JE28:221 ; Antigonadotrophic JE28:221 ; Antihyperlipoproteinaemic JBH ; Antiinflammatory; Antileukemic PJB1(2):287 ; Antilymphomic PJB1(2):287 ; Antimutagenic 250 ug/ml JAFC37:1365 ; Antiophidic 2.3 mg mus EMP5:363 ; Antioxidant IC44=10 uM JMF5:1 ; Antiprogestational JE28:221 ; Antiprostaglandin 30 mg/day/12 wks FT68(4):291 ; Antiprostatadenomic M11 ; Antiprostatitic 10-20 mg 3 x/day/orl man; Antipyretic HDN ; Antitumor (Breast) PS131:95 ; Antitumor (Cervix) PJB1(2):287 ; Antitumor (Lung) PJB1(2):287 ; Antiviral PS75:161 ; Apoptotic X17350814 ; Artemicide LC50=110 ppm PC29(5):1667 ; Cancer-Preventive 525 ; Candidicide QJC28:155 ; Caspase-8-Inducer X17358014 ; Estrogenic PHM9:52 ; Febrifuge HDN ; Gonadotrophic JE28:221 ; Hepatoprotective PMP23:60 ; Hypocholesterolemic 2-6 g/man/day/orl M30 9-3,330 mg/man/day/orl MAR ; Hypoglycemic JE27:243 ; Hypolipidemic 2-6 g/day; Pesticide DUKE1992B ; Spermicide JE28:221 ; Ubiquiot JBH ; Ulcerogenic 500 mg/kg ipr rat FT63(1):3

BETA-STORESIN Resin, Exudate, Sap: DUKE1992A

No activity reported.

CINNAMIC-ACID Resin, Exudate, Sap 20,000 - 150,000 ppm DUKE1992A

Aldose-Reductase-Inhibitor 4 ug/ml (weak activity) SKN43:99 ; Allergenic M&R317 ; Anesthetic DUKE1992B ; Antibacterial MAR ; Antiinflammatory PMP25:55 ; Antimutagenic EMP6:235 ; Antispasmodic JBH ; Cancer-Preventive 525 ; Choleretic DUKE1992B ; Dermatitigenic JBH ; FLavor FEMA 4-40 ARC ; Fungicide DUKE1992B ; Herbicide DUKE1992B ; Laxative DUKE1992B ; Lipoxygenase-Inhibitor RWG141 ; Pesticide DUKE1992B ; Tyrosinase-Inhibitor ID50=700 uM; Vermifuge JE26:81

CINNAMIC-ALCOHOL Resin, Exudate, Sap: DUKE1992A

Allergenic M&R370 ; FEMA 3-700 ARC ; Irritant ZEB

CINNAMYL-CINNAMATE Resin, Exudate, Sap 50,000 - 100,000 ppm DUKE1992A

FLavor FEMA <1 ARC

EO Resin, Exudate, Sap 5,000 - 10,000 ppm DUKE1992A

No activity reported.

ETHANOL Resin, Exudate, Sap: DUKE1992A

Allergenic M&R722 ; Anesthetic 4,000 orl cat BBE 6,000 orl rat BBE ; Anhydrotic M29 ; Antiatherosclerotic PMID11020457 ; Antibacterial MAR ; Antipruritic MAR ; Antiseptic M11 ; CNS-Depressant MAR ; Expectorant SHT ; Hepatotoxic M29 ; Hypertensive >1 drink/day X7760897 ; Hypnotic Antidote=Naloxone M29 ; Hypocalcemic 4,000 orl rat BBE ; Hypotensive 1 drink/day X7760897 ; Mucotropic SHT ; Neurolytic M11 ; Pesticide DUKE1992B ; Rubefacient M29 ; Sclerosant M29 ; Surfactant SHT ; Teratogenic 6,000 orl dog BBE ; Tremorilytic MAR ; Ulcerogenic 5 ml/kg (50%) orl rat

ETHYL-CINNAMATE Resin, Exudate, Sap: DUKE1992A

FLavor FEMA 4-40 ARC ; Nematicide MLC=1,000 uM SZ44:183


No activity reported.

OLEANOLIC-ACID Resin, Exudate, Sap: DUKE1992A

Abortifacient DUKE1992B ; Antiallergic LAF351 ; Antiarrhythmic 40 mg/kg X15070161 ; Antiatherosclerotic LAF351 ; Antibacterial MIC=625-1,250 ug/ml JNP59:987 ; Anticarcinomic AJC31:37 ; Anticariogenic LAF ; Anticomplement IC40-50 0.01 mM/l gpg HH2 IC80-90 0.05 mM/l gpg HH2 ; Antiedemic IC36=40 mg/kg ipr rat DFN:159 ; Antifertility PMP24:113 ; Antigingivitic MIC=625-1,250 ug/ml JNP59:987 ; Antihepatotoxic PM56(2):173 ; AntiHIV EC50=1.7 ug/ml JNP61:1090 IC50=21.8 ug/ml; Antihyperlipidemic JE49:57 ; Antiinflammatory 40 mg/kg ipr JNP54:455 ; Antiischemic 40 mg/kg X15070161 ; Antileukemic AJC31:37 ; Antileukotriene IC50=17 uM X11085357 ; Antimalarial IC50=70-89 ug/ml PR13:115 ; Antinephritic IC50=19-24 uM X12898427 ; Antioxidant IC46=10 uM JMF5:1 BCI28:735 ; Antiperiodontic MIC=625-1,250 ug/ml JNP59:987 ; Antiperoxidant IC30=200 ug/ml JAF50:2993 ; AntiPGE2 IC50=24 uM X11085357 ; Antiplaque MIC=625-1,250 ug/ml JNP59:987 ; Antiplasmodial IC50=70-89 ug/ml PR13:115 ; Antisarcomic DUKE1992B ; Antiseptic MIC=625-1,250 ug/ml JNP59:987 ; AntiTGF-beta IC50=19-24 uM X12898427 ; Antitumor LAF351 ; Antitumor (Breast) AJC31:37 ; Antitumor (Colon) AJC31:37 ; Antitumor (Kidney) AJC31:37 ; Antitumor (Lung) AJC31:37 ; Antitumor (Pancreas) AJC31:37 ; Antiulcer >carbenoxolone PJB1(1):181 ; Antiviral EC50=1.7 ug/ml JNP61:1090 IC50=21.8 ug/ml JNP61:1090 ; Aromatase-Inhibitor FIT68:387 ; Beta-Blocker X15070161 ; Beta-Glucuronidase-Inhibitor ~100 mg/kg BO2 ; Cancer-Preventive 525 ; Cardioprotective 40 mg/kg X15070161 ; Cardiotonic; COX-2-Inhibitor IC50=295 uM/ JNP61:1212 ; Cyclooxygenase-Inhibitor DUKE1992B ; Diuretic LAF ; Elastase-Inhibitor IC50=~15 uM BO2 ; Hepatoprotective ACM:211 ; Hypolipemic LAF351 ; Hypotensive X15070161 ; Immunomodulator LAF351 ; Leucocytogenic X13678231 ; NF-kB-Inhibitor X14966369 ; Phagocytotic LAF351 ; Piscicide WOI ; Prostaglandin-Synthesis-Inhibitor igs mus; Sedative LAF351 ; Uterotonic; Vasopressor X15070161

PHENYLETHYLENE Resin, Exudate, Sap: DUKE1992A

No activity reported.


No activity reported.

PHENYLPROPYL-CINNAMATE Resin, Exudate, Sap 100,000 ppm; DUKE1992A

No activity reported.


Analgesic MEDSCAPE'89 ; Anticancer JAF47:397 ; Anticonvulsant HDN ; Antioxidant 7 x quercetin JAF47:397 ; Antiradicular JAF47:397 ; Antispasmodic GMJ ; Antitumor JAF47:397 ; Antitumor-Promoter JAF47:397 ; Bruchifuge 382 ; Cancer-Preventive JAF47:397 ; Carcinogenic M11 ; Ileorelaxant FT1990:508 ; Mutagenic DUKE1992B ; Pesticide DUKE1992B

STORESIN Resin, Exudate, Sap 330,000 - 500,000 ppm DUKE1992A

No activity reported.


No activity reported.

STYRACIN Resin, Exudate, Sap 50,000 - 100,000 ppm DUKE1992A

No activity reported.

STYRENE Essential Oil: DUKE1992A

Irritant DUKE1992B ; Narcotic M11 ; Perfumery ARC

STYROL Resin, Exudate, Sap: DUKE1992A

No activity reported.


Anthelmintic JNP59:205 ; Antibacterial JE26:74 ; Anticancer JAF47:397 ; Anticariogenic JNP59:205 ; Antidiarrheic DUKE1992B ; Antidysenteric DUKE1992B ; Antihepatotoxic JNP59:205 ; AntiHIV JNP59:205 ; Antihypertensive JNP59:205 ; Antilipolytic JNP59:205 ; Antimutagenic DUKE1992B ; Antinephritic CPB38:1049 ; Antiophidic EMP5:363 ; Antioxidant 1/3 quercetin JAF47:397 IC50=1.44 ug/ml CPB38:1051 ; Antiradicular 1/3 quercetin JAF47:397 500 mg/kg/day orl mus CPB38:1049 ; Antirenitic CPB38:1049 ; Antitumor; Antitumor-Promoter JAF47:397 ; Antiulcer JNP59:205 ; Antiviral; Cancer-Preventive HG22:14 ; Carcinogenic AHP156 ; Chelator JNP59:205 ; Cyclooxygenase-Inhibitor JNP59:205 ; Glucosyl-Transferase-Inhibitor JNP59:205 ; Hepatoprotective DUKE1992B ; Immunosuppressant RWG29 ; Lipoxygenase-Inhibitor JNP59:205 ; MAO-Inhibitor JNP59:205 ; Ornithine-Decarboxylase-Inhibitor JNP59:205 ; Pesticide DUKE1992B ; Psychotropic CPB38:1049 ; Xanthine-Oxidase-Inhibitor JNP59:205

VANILLIN Resin, Exudate, Sap: DUKE1992A

Allelochemic IC50=4.26 mM 438 ; Allergenic M&R416 ; Antianemic X15180869 ; Anticancer JAF47:397 ; Antidrepanocytic X15180869 ; Antiescherichic 10-100 mmol/l X15186447 ; Antilactobacillic X15186447 ; Antilisteria X14968973 ; Antimutagenic EMP6:235 ; Antioxidant =ascorbic acid; Antipolio EMP5:194 ; Antiradicular 7 x quercetin JAF47:397 ; Antisickling; Antitumor JAF47:397 ; Antitumor-Promoter JAF47:397 ; Antiviral EMP5:194 ; Antiyeast 8-30 mM X14968976 ; Bacteristat 10-40 mmol/l X15186447 ; Cancer-Preventive 525 ; Candidicide 8-20 mM X14968976 ; Choleretic RIN ; FLavor FEMA 50-20,000 ARC ; Fungicide JBH ; Immunosuppressant RWG29 ; Insectifuge? MAR ; Irritant; Perfumery; Pesticide DUKE1992B

WATER Resin, Exudate, Sap 150,000 - 300,000 ppm DUKE1992A

No activity reported.

The source of the experience


Concepts, symbols and science items



Science Items

Activities and commonsteps






382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.

438: Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.

525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.

ACM:211: Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 211.

AHP156: Jim Duke's personal files

AJC31:37: Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.

ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.

BBE: Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.

BCI28:735: Balanehru, S. and Nagarajan, B. 1992. Intervention of Adriamycin Induced Free Radical Damage. Biochemistry International 28(4): 735-744, 1992.

BO2: Jim Duke's personal files

CPB38:1049: Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.

CPB38:1051: Jim Duke's personal files

DFN:159: Jim Duke's personal files

DFN:160: Jim Duke's personal files

DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

EMP5:194: Economic & Medicinal Plant Research, 5: 194.

EMP5:363: Economic & Medicinal Plant Research, 5: 363.

EMP6:235: Economic & Medicinal Plant Research, 6: 235.

FIT68:387: Jim Duke's personal files

FT1990:508: Jim Duke's personal files

FT63(1):3: Jim Duke's personal files

FT68(4):291: Jim Duke's personal files

GMJ: Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.

HDN: Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.

HG22:14: HerbalGram No. 22 - Spring 1990, page 14.

HH2: Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

JA6(4):40: Jim Duke's personal files.

JAF47:397: Jim Duke's personal files

JAF50:2993: Jim Duke's personal files

JAFC37:1365: Jim Duke's personal files

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JE26:74: Jim Duke's personal files

JE26:81: Jim Duke's personal files

JE27:243: Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.

JE28:221: Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.

JE49:57: Jim Duke's personal files

JMF5:1: Jim Duke's personal files

JNP54:455: Aquino, R., De Feo, V., De Simone, F., Pizza, C.*, and Cirino, G. Plant Metabolites. New Compounds And Anti-Inflammatory Activity Of Uncaria tomentosa. Journal of Natural Products, 54(2): 453-459, 1991.

JNP59:205: Jim Duke's personal files

JNP59:987: Jim Duke's personal files

JNP61:1090: Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.

JNP61:1212: Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.

LAF: Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.

LAF351: Jim Duke's personal files

M&R317: Jim Duke's personal files

M&R370: Jim Duke's personal files

M&R416: Jim Duke's personal files

M&R722: Jim Duke's personal files

M11: Merck 11th Edition

M29: Martindale's 29th

M30: Martindale's 30th

MAR: Martindale's 28th

MEDSCAPE'89: Jim Duke's personal files

PC29(5):1667: Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.

PHM9:52: Jim Duke's personal files

PJB1(1):181: Jim Duke's personal files

PJB1(2):287: Jim Duke's personal files

PM56(2):173: Jim Duke's personal files

PMID11020457: Jim Duke's personal files

PMP23:60: Jim Duke's personal files

PMP24:113: Jim Duke's personal files

PMP25:55: Jim Duke's personal files

PR13:115: Jim Duke's personal files

PS131:95: Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.

PS75:161: Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.

QJC28:155: Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.

RIN: Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.

RWG141: Jim Duke's personal files

RWG29: Jim Duke's personal files

SHT: Schulz, V, Hansel, R and Tyler, VE. 1998. Rational Phytotherapy - A Physician's Guide to Herbal Medicine. 3rd ed. 1st English Edition. Translated by Terry C. Telger. Springer Verlag, Heidelberg. 306 pp.

SKN43:99: Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.

SZ44:183: Shoyakugaku Zasshi, 44: 183.

WOI: ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.

X11085357: Jim Duke's personal files

X11988857: Jim Duke's personal files

X12898427: Jim Duke's personal files

X13678231: Jim Duke's personal files

X14966369: Jim Duke's personal files

X14968973: Jim Duke's personal files

X14968976: Jim Duke's personal files

X15070161: Jim Duke's personal files

X15180869: Jim Duke's personal files

X15186447: Jim Duke's personal files

X16719518: Jim Duke's personal files

X17350814: Jim Duke's personal files

X17358014: Jim Duke's personal files

X7760897: Jim Duke's personal files

ZEB: Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.

ppm = parts per million
tr = trace


Sat Oct 31 10:50:15 EDT 2015