Causes Of Chronic Non-Infectious Diarrhoea In Infants Less Than 6 Months Of Age: Rarely Recognized Entities
Type of Spiritual Experience
If you know the cause, you can help prevent the symptoms, however, this paper does not cover the root causes of each of the underlying problems found
A description of the experience
J Ayub Med Coll Abbottabad. 2017 Jan-Mar;29(1):78-82.
Causes Of Chronic Non-Infectious Diarrhoea In Infants Less Than 6 Months Of Age: Rarely Recognized Entities.
Mushtaq I1, Cheema HA1, Malik HS1, Waheed N1, Hashmi MA1, Malik HS1.
Department of Paediatric Gastroenterology & Hepatology, The Children's Hospital and Institute of Child Health Lahore, Pakistan.
Non-infectious causes of chronic diarrhoea are important and easily missed. The study was done with the objectives to identify different causes of chronic non-infectious diarrhoea in infants less than 6 months of age.
All patients less than 6 months of age presenting for the first time to a Paediatric Gastroenterology tertiary care centre with a history of chronic diarrhoea and negative stool cultures were enrolled over a period of 8 months. Demographical profile and various factors under observation were recorded in this observational study. Collected data was analysed using SPSS version 20. Chi square test was applied as a test of significance for any qualitative variable, p value (p<0.05) was taken as significant.
Among 72 enrolled patients, female to male ratio was1.05:1. Age at onset of symptoms was between 15 days to 6 months. Aetiology found was
- Cow's milk protein allergy (CMPA) in 58 (80.6%),
- Primary intestinal lymphangiectasia (PIL) 6 (8.3%),
- Cystic fibrosis (CF) 3 (4.2%),
- Immunodeficiency (SCID) 2 (2.8%), 1 (1.4%) for each Abetalipoproteinemia (ABL),
- Glucose galactose malabsorption (GGM) and
- Congenital chloride diarrhoea (CCD).
Among noninfectious causes of chronic diarrhoea in early infancy, cow's milk protein allergy is most common followed by Primary intestinal lymphangiectasia and Cystic fibrosis.
Abetalipoproteinemia; Chronic Diarrhoea; Congenital Chloride Diarrhoea; Cow’s Milk Protein Allergy; Cystic Fibrosis; Glucose Galactose Malabsorption; Immunodeficiency; Primary Intestinal Lymphangiectasia