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Observations placeholder

Antimicrobial activity of plant extracts against sexually transmitted pathogens

Identifier

019349

Type of Spiritual Experience

Background

Bridelia retusa is a species of Bridelia found in Bangladesh, Nepal, India, Sri Lanka, southern China, Indochina, and Sumatra.  The bark of the roots is used in traditional medicine.

A description of the experience

Nat Prod Res. 2015;29(16):1562-6. doi: 10.1080/14786419.2014.983919. Epub 2014 Nov 27.

Antimicrobial activity of plant extracts against sexually transmitted pathogens.

Jadhav N1, Kulkarni S, Mane A, Kulkarni R, Palshetker A, Singh K, Joshi S, Risbud A, Kulkarni S.

 

  • 1a Department of Virology , National AIDS Research Institute , Pune , India.

Abstract

Comprehensive management of sexually transmitted infections (STIs) using vaginal or rectal microbicide-based intervention is one of the strategies for prevention of HIV infection.

Herbal products have been used for treating STIs traditionally. Herein, we present in vitro activity of 10 plant extracts and their 34 fractions against three sexually transmitted/reproductive tract pathogens - Neisseria gonorrhoeae, Haemophilus ducreyi and Candida albicans.

The plant parts were selected; the extracts/fractions were prepared and screened by disc diffusion method. The minimum inhibitory and minimum cidal concentrations were determined. The qualitative phytochemical analysis of selected extracts/fractions showing activity was performed.  Of the extracts/fractions tested,

  • three inhibited C. albicans,
  • ten inhibited N. gonorrhoeae and
  • five inhibited H. ducreyi growth.

Our study demonstrated that Terminalia paniculata Roth. extracts/fractions inhibited growth of all three organisms. The ethyl acetate fraction of Syzygium cumini Linn. and Bridelia retusa (L.) Spreng. extracts was found to inhibit N. gonorrhoeae at lowest concentrations.

KEYWORDS:

Candida albicans; Haemophilus ducreyi; Neisseria gonorrhoeae; anti-STI activity; microbicide; plant extracts/fractions

PMID:

25427632

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Candidiasis
Chancroid
Gonorrhea

Suppressions

Java plum

Commonsteps

References