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Observations placeholder

Antifungal activities and chemical composition of some medicinal plants

Identifier

023032

Type of Spiritual Experience

Background

Bupleurum falcatum, also known as sickle-leaved hare's-ear, Chinese thoroughwax, sickle hare's ear and sickle-leaf hare's ear, is a species of flowering plant in the Apiaceae family.  It is endemic to Europe and Western Asia.

Bupleurum falcatum has been used in Chinese medicine for over 2,000 years.

A description of the experience

J Mycol Med. 2014 Jun;24(2):e1-8. doi: 10.1016/j.mycmed.2014.02.006. Epub 2014 Apr 24. Antifungal activities and chemical composition of some medicinal plants.  Mohammadi A1, Nazari H1, Imani S2, Amrollahi H3.

1Department of biochemistry, faculty of medicine, Semnan university of medical sciences, Semnan, Iran.

2Department of microbiology, faculty of medicine, Semnan university of medical sciences, Semnan, Iran.

3Department of microbiology, faculty of medicine, Semnan university of medical sciences, Semnan, Iran. Electronic address: hadiamrollahi@gmail.com.

The use of and search for drugs and dietary supplements derived from plants have accelerated in recent years. Ethnopharmacologists, botanists, microbiologists and natural-products scientists are combing the earth for phytochemicals and leads, which could be developed for treatment of infectious diseases.

The aim of this study was to investigate the antifungal activities of the essential oils of some medicinal plants such as

  • Stachys pubescens,
  • Thymus kotschyanus,
  • Thymus daenensis and
  • Bupleurum falcatum

against Fusarium oxysporum, Aspergillus flavus and Alternaria alternata.

The essential oils were used to evaluate their MICs and MFCs compared to the amphotricin B as a standard drug. The essential oils were also analyzed by GC/MS.

Essential oils isolated from the

  • S. pubescens,
  • T. kotschyanus and
  • B. falcatum

showed strong antifungal activities. The essential oil of T. daenensis exhibited a moderate activity against the selected fungi in comparison with the other plants' essential oils. In addition, the results showed that 26, 23, 22 and 15 components were identified from the essential oils of T. kotschyanus, S. pubescens, T. daenensis and B. falcatum, respectively.

These oils exhibited a noticeable antifungal activity against the selected fungi. Regarding obtained results and that natural antimicrobial substances are inexpensive and have fewer side effects, they convey potential for implementation in fungal pathogenic systems.

PMID: 24768063

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Commonsteps

Aromatherapy

References