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Observations placeholder

Dr Duke's list of Chemicals and their Biological Activities in: Betula papyrifera (Betulaceae)

Identifier

019570

Type of Spiritual Experience

Background

A description of the experience

Chemicals and their Biological Activities in: Betula papyrifera (Betulaceae)

Chemicals

BETULIN Bark 15,000 ppm; JAD Heart Wood: JAD

Anticarcinomic PJB1(3):232 ; Antifeedant JAF38:494 ; Antiflu JNP67:344 ; AntiHIV 6.1 uM JNP66:263 ; Antiinflammatory PM61:9 ; Antitumor JBH ; Antiviral; Aphidifuge JAF38:493 ; Cytotoxic 600 ppm DUKE1992B 8.6 uM JNP66:263 ; Hypolipemic PMP23:49 ; Prostaglandin-Synthesis-Inhibitor IC50=119 uM YHH30:621 ; Topoisomerase-II-Inhibitor IC50=38.6 uM JNP64:1545

BETULINIC-ACID Bark: JAD

Anthelmintic X11315752 ; Antibacterial X10630117 ; Anticancer JBH ; Anticarcinomic JBH ; Antiedemic X7701004 ; AntiHIV 14.8 uM EC50=2.0 ug/ml JNP61:1090 IC50=6.5 ug/ml; Antiinflammatory PM61:9 ; Antileukemic X9353895 ; Antimalarial IC50=19-26 ug/ml PR13:115 ; Antimelanomic NYT3/28/95 ; Antinociceptive; Antiplasmodial PR13:115 ; Antitumor JBH ; Antiviral 14.8 uM; Apoptotic; Cytotoxic 16.4 uM JNP66:263 50-100 ppm BPCC ; Phospholipase-A2-Inhibitor X11684183 ; Prostaglandin-Synthesis-Inhibitor 200 ug/ml PC48:495 IC50=101 uM YHH30:621

The source of the experience

Dr Dukes plant database

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Suppressions

White birch

Commonsteps

References

BPCC: Biosyn. Prod. Cancer Chemotherapy (Petit et al)

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

JAD: Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.

JAF38:493: Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494.

JAF38:494: Jim Duke's personal files

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JNP61:1090: Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.

JNP64:1545: Jim Duke's personal files

JNP66:263: Jim Duke's personal files

JNP67:344: Jim Duke's personal files

NYT3/28/95: New York Times, 3/28/95.

PC48:495: Dunstan, C. A., Liu, B., Welch, C. J., Perera, P., Bohlin, L. 1998. Alphitol, a Phenolic Substance from Alphitonia zizyphoides which Inhibits Prostaglandin Biosynthesis in vitro. Phytochemistry, 48(3): 495-497.

PJB1(3):232: Jim Duke's personal files

PM61:9: Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.

PMP23:49: Jim Duke's personal files

PR13:115: Jim Duke's personal files

X10630117: Jim Duke's personal files

X11315752: Jim Duke's personal files

X11684183: Jim Duke's personal files

X7701004: Jim Duke's personal files

X9353895: Jim Duke's personal files

YHH30:621: Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.

ppm = parts per million
tr = trace