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Yerba mate, passion fruit and herpes simplex



Type of Spiritual Experience


Rubus imperialis is a south american fruit in the same family as blackberries and raspberries


A description of the experience

Evaluation of antiviral activity of South American plant extracts against herpes simplex virus type 1 and rabies virus. - Müller V, et al. Departamento de Ciências Farmacêuticas, CCS, Universidade Federal de Santa Catarina (UFSC), Florianópolis 88040-900, SC, Brasil.

This paper describes the screening of different South American plant extracts and fractions. Aqueous and organic extracts were prepared and tested for antiherpetic (HSV-1, KOS and 29R strains) and antirabies (PV strain) activities.

The evaluation of the potential antiviral activity of these extracts was performed by using an MTT assay for HSV-1, and by a viral cytopathic effect (CPE) inhibitory method for rabies virus (RV). The results were expressed as 50% cytotoxicity (CC(50)) for MTT assay and 50% effective (EC(50)) concentrations for CPE, and with them it was possible to calculate the selectivity indices (SI = CC(50)/EC(50)) of each tested material.

From the 18 extracts/fractions tested, six extracts and four fractions showed antiviral action. Ilex paraguariensis [Yerba mate], Lafoensia pacari, Passiflora edulis [passion fruit], Rubus imperialis and Slonea guianensis showed values of SI > 7 against HSV-1 KOS and 29-R strains and Alamanda schottii showed a SI of 5.6 against RV, PV strain.

The source of the experience


Concepts, symbols and science items



Science Items

Activities and commonsteps



Herpes simplex
Viral infection


Passion fruit
Yerba Mate