Observations placeholder

Yerba mate, passion fruit and herpes simplex

Identifier

005370

Type of Spiritual Experience

Background

Rubus imperialis is a south american fruit in the same family as blackberries and raspberries

 

A description of the experience

Evaluation of antiviral activity of South American plant extracts against herpes simplex virus type 1 and rabies virus. - Müller V, et al. Departamento de Ciências Farmacêuticas, CCS, Universidade Federal de Santa Catarina (UFSC), Florianópolis 88040-900, SC, Brasil.

This paper describes the screening of different South American plant extracts and fractions. Aqueous and organic extracts were prepared and tested for antiherpetic (HSV-1, KOS and 29R strains) and antirabies (PV strain) activities.

The evaluation of the potential antiviral activity of these extracts was performed by using an MTT assay for HSV-1, and by a viral cytopathic effect (CPE) inhibitory method for rabies virus (RV). The results were expressed as 50% cytotoxicity (CC(50)) for MTT assay and 50% effective (EC(50)) concentrations for CPE, and with them it was possible to calculate the selectivity indices (SI = CC(50)/EC(50)) of each tested material.

From the 18 extracts/fractions tested, six extracts and four fractions showed antiviral action. Ilex paraguariensis [Yerba mate], Lafoensia pacari, Passiflora edulis [passion fruit], Rubus imperialis and Slonea guianensis showed values of SI > 7 against HSV-1 KOS and 29-R strains and Alamanda schottii showed a SI of 5.6 against RV, PV strain.

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Herpes simplex
Viral infection

Suppressions

Passion fruit
Yerba Mate

Commonsteps

References