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Observations placeholder

Dr Duke's list of Chemicals and their Biological Activities in: Lippia alba (MILL.) N.E. BR. (Verbenaceae) -- White Lippia



Type of Spiritual Experience


A description of the experience

Chemicals and their Biological Activities in: Lippia alba (MILL.) N.E. BR. (Verbenaceae) -- White Lippia


1,8-CINEOLE Plant: GMJ

(-)-Chronotropic 87 nl/ml HH2 ; (-)-Inotropic HH2 ; Acaricide LC100=6 uM; Allelopathic; Allergenic M&R486 ; Anesthetic DUKE1992B ; Anthelmintic JBH ; Antiacetylcholinesterase IC50=41 ug/ml JAF46:3434 ; Antiallergic JFH33(6):569 ; Antibacterial 50 ppm; Antibronchitic PR14:240 ; Anticariogenic JNP59:823 ; Anticatarrh M29 ; Anticholinesterase IC50=50-70; Antifatigue JAR8:2 ; Antihalitosic AH12(4):17 ; Antiinflammatory EJP331:253 ; Antilaryngitic DUKE1992B ; Antinociceptive PR14:401 ; Antipharyngitic DUKE1992B ; Antiplaque X12537346 ; Antirheumatic PR14:240 ; Antirhinitic DUKE1992B ; Antiseptic JBH ; Antisinusitic PR14:240 ; Antispasmodic SHT158 ; Antistaphylococcic 50 ppm JAR8:2 ; Antitussive; Antiulcer X11281182 ; Candidicide LAF337 ; Carcinogenic ZEB ; Choleretic DUKE1992B ; CNS-Stimulant DUKE1992B ; Convulsant JAR8:2 ; Counterirritant M29 ; Cytochrome-P450-Inducer MED'95 ; Decongestant; Degranulant 0.3 ul/ml EJP331:253 ; Dentifrice M29 ; Edemagenic inj; Expectorant JBH ; FLavor FEMA 1-200 ARC ; Fungicide SHT158 ; Gastroprotective X11281182 ; Gram(+)icide JAR8:2 ; Gram(-)icide JAR8:2 ; Hepatotonic DUKE1992B ; Herbicide IC50=78 uM TOX ; Hypotensive DUKE1992B ; Inflammatory inj EJP331:253 ; Insectifuge; Irritant RIN ; Myorelaxant CAN ; Nematicide NIG ; Neurotoxic JAR8:2 ; P450-Inducer MED'95 ; Pediculicide 2.3 x pyrethrin JAF52:2507 ; Perfume ARC ; Pesticide DUKE1992B ; Rubefacient M29 ; Secretogogue SHT158 ; Sedative; Spasmogenic JAR8:2 ; Surfactant SHT158 ; Testosterone-Hydroxylase-Inducer MED'95 ; Transdermal X14703969 ; Trichomonicide LD100=1,000 ug/ml FT67:279


Anthelmintic LAF ; Hirudicide LAF ; Nematicide LAF ; Pesticide DUKE1992B


Allelochemic DUKE1992B ; Allergenic M&R523 ; Antiacne JAR12:99 ; Antibacterial; Antifeedant JAF45:3276 ; Antiflu EMP5:195 ; Antiinflammatory 500 mg/kg; Antipneumonic X16248573 ; Antiseptic X16248573 ; Antispasmodic; Antistaphylococcic X16248573 ; Antiviral EMP5:195 ; Cancer-Preventive 525 ; Coleoptophile DUKE1992B ; Expectorant MIK ; FLavor FEMA 15-150 ARC ; Herbicide IC50=30 uM TOX ; Insecticide 0.82 uM/fly JAF50:4576 ; Insectifuge 50 ppm; Insectiphile JSPR22:141 ; Irritant JBH ; P450-2B1-Inhibitor IC50=0.087 uM X9242356 ; Perfumery ARC ; Pesticide DUKE1992B ; Sedative LRN-JUN90 ; Spasmogenic; Tranquilizer LRN-JUN90 ; Transdermal X7199340


No activity reported.


Allelopathic; Analgesic; Anesthetic; Antiacne NIG ; Antidiarrheic 500 ug/ml WO2 ; Antidysenteric WO2 ; Antiemetic 100-200 mg man orl KCH ; Antifeedant IC50=5,000 ppm diet 438 ; Antifibrositic MAR ; Antineuralgic MAR ; Antipruritic M11 ; Antiseptic M11 ; Antispasmodic ED50=0.075 mg/ml FT59:465 ; Cancer-Preventive 525 ; Carminative JPP46:16 ; CNS-Stimulant JE26:74 ; Convulsant RJH ; Cosmetic JBH ; Counterirritant MAR ; Decongestant NIG ; Deliriant M11 ; Ecbolic DUKE1992B ; Emetic DUKE1992B ; Epileptigenic CAN ; Expectorant M29 ; Fungicide ED50=2.7 mM TOX ; Herbicide IC50=3.3-180 mM 438 ; Insect-Repellent DUKE1992B ; Insectifuge; Irritant JBH ; Nematicide MLC=1 mg/ml SZ44:183 ; Occuloirritant M&R367 ; P450-2B1-Inhibitor IC50=7.89 uM X9242356 ; Pesticide DUKE1992B ; Respirainhibitor M11 ; Respirastimulant KCH ; Rubefacient; Stimulant RJH ; Transdermal; Verrucolytic NIG ; Vibriocide 500 ug/ml WO2


Allergenic; Antiallergenic; Antiallergic KCH ; Antianaphylactic PJB1(2):266 ; Antibacterial; Anticancer X15931590 ; Antihelicobacter X14506036 ; Antiherpetic X17199238 ; Antihistaminic KCH ; Antiinflammatory X18409048 ; Antileishmanic; Antioxidant X12615076 ; Antiseptic 5.2 x phenol; Antishock KCH ; Antispasmodic TEU ; Antitumor; Antitumor (Colon) X17199238 ; Antitumor (Liver) X17199238 ; Antitumor (Skin) X17199238 ; Antiulcer X14506036 ; Antiviral X17199238 ; Apoptotic; Barbituate-Synergist PJB1(2):266 ; Bronchorelaxant KCH ; Calcium-Antagonist X18484528 ; Cancer-Preventive 525 ; Carcinogenic X12637974 ; Caspase-3-Inducer X15931590 ; Chemopreventive; Cytotoxic X19876560 ; Estrogenic X12495555 ; Expectorant KCH ; FLavor FEMA 4-170 ARC ; Fungicide MIC 625 ug/ml; Glaucomagenic JAR10:7 ; Glutathionigenic; Herbicide IC50=115 uM TOX ; Myorelaxant 200 mg/kg; Nematicide IC52=100 ug/ml NIG MLC=100-260 ug/ml SZ44:183 ; NF-kB-Inhibitor X18409048 ; NO-Inhibitor X18409048 ; P450-2B1-Inhibitor IC50=1.19 uM X9242356 ; Perfumery M11 ; Pesticide DUKE1992B ; Prostatitigenic 185 mg/kg/day/3 ms JAR10:7 ; Sedative 1 mg/kg TEU ED 1-32 mg/kg W&W ; Teratogenic JNP39:446 ; Trichomonicide LD100=150 ug/ml FT67:279 ; Trypanocide X17686189 ; Tyrosinase-Inhibitor ID50=1,500 uM JAF51:2837 ID50=1.5 mM JAF47:4574

EO Leaf 1,200 ppm; GMJ

No activity reported.


Allergenic; Anthelmintic MAD ; Antibacterial MBC=800 ug/ml JNP49:5750 MIC=400 ug/ml JAF41:1103 MIC=64 ug/ml PR14:303 ; Anticancer (Pancreas) IC50=265 uM LIP32:151 ; Anticariogenic MIC=400 ug/ml JAF41:1103 ; Antimelanomic IC50=150 uM/l JN127:668 ; Antisalmonella MIC=400 ug/ml JNP49:5750 ; Antiseptic 400-800 ug/ml JNP49:5750 7 x phenol W&W MIC=64 ug/ml PR14:303 ; Antispasmodic JEO2:185 ; Antitubercular PR14:303 ; Antitumor JAF43:2144 ; Antitumor (Pancreas) IC50=265 uM LIP32:151 ; Ascaricide MAD ; Cancer-Preventive 525 ; Candidicide DUKE1992B ; CNS-Stimulant HHB ; Embryotoxic DUKE1992B ; Emetic 3 x ipecac LRN-SEP97 ; Expectorant MAD ; FLavor FEMA 1-10 ARC ; Fungicide IC93=2 mM 438 ; Herbicide IC100-2,000 uM TOX ; Insectifuge 50 ppm JSPR22:141.1986 ; Insectiphile M11 ; Mycobactericide MIC=64 ug/ml PR14:303 ; Nematicide IC86=100 ug/ml NIG MLC=1,000 ug/ml SZ44:183 ; Perfumery M11 ; Pesticide DUKE1992B ; Sedative; Trichomonicide LD100=300 ug/ml FT67:279


Acaricide LC100=8 uM JAF50:4586 ; AChE-Inhibitor 453 ; Allelochemic JAF45:3276 ; Allergenic 1/20th carene M&R521 ; Antiacetylcholinesterase IC22-26=1.2 mM JAF45:677 ; Antiadenomic ACT13:64 ; Antialzheimeran? 453 ; Antiasthmatic X15598576 ; Antibacterial RIE12:5 ; Anticancer AEM401:131 ; Antiesophagitic ACT13:64 ; Antifeedant JAF45:3276 ; Antiflu EMP5:195 ; Antiinflammatory X15598576 ; Antilithic M29:1064 ; Antilymphomic X15778119 ; Antimetastatic (Stomach) ACT13:64 ; Antimutagenic EMP6:235 ; Antiobesity X15862904 ; Antiseptic JAF44:2802 ; Antispasmodic ED50=0.197 mg/ml FT59:465 ; Antitumor; Antitumor (Breast) AEM401:131 ; Antitumor (Colon) ACT13:64 ; Antitumor (Pancreas) AEM401:131 ; Antitumor (Prostate) AEM401:131 ; Antitumor (Stomach) ACT13:64 ; Antiviral; Apoptotic X14998133 ; Bronchoprotectant X15598576 ; Cancer-Preventive 525 ; Candidistat JAF40:2330 ; Chemopreventive AEM401:131 ; Cholesterolytic X18072821 ; Detoxicant; Enterocontractant JAR4:22 ; Expectorant; FLavor PJB1(3):242 ; Fungiphilic JAF43:2283 ; Fungistat JAF40:2330 ; GST-Inducer X1438594 ; Herbicide IC50=45 uM TOX ; Histaminic X15862904 ; Immunomodulator X15778119 ; Insecticide 0.37 uM/fly; Insectifuge 382 ; Interleukin-6-Inhibitor X17867636 ; Irritant; Lipolytic X15862904 ; Myorelaxant 50 mg/kg X12587690 ; Nematicide IC=100 ug/ml NIG ; NO-Genic X15778119 ; Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet) BO2 ; Ozone-Scavenger X15598576 ; P450-Inducer; Peristaltic X18072821 ; Pesticide DUKE1992B ; Photosensitizer RIN ; Sedative ED=1-32 mg/kg W&W ; Transdermal X7199340


No activity reported.


No activity reported.


Antibacterial IWU ; Antispasmodic JAR10:7 ; Pesticide DUKE1992B ; Termiticide LD100=5 mg/g JAF50:1389

The source of the experience


Concepts, symbols and science items



Science Items

Activities and commonsteps



White lippia



382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.

438: Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.

453: Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.

525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.

ACT13:64: Jim Duke's personal files

AEM401:131: Jim Duke's personal files

AH12(4):17: American Health, 12(4): 17, 1993.

ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.

BO2: Jim Duke's personal files

CAN: Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

EJP331:253: Jim Duke's personal files

EMP5:195: Economic & Medicinal Plant Research, 5: 195.

EMP6:235: Economic & Medicinal Plant Research, 6: 235.

FT59:465: Fitoterapia No.59-1984.

FT67:279: Jim Duke's personal files

GMJ: Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.

HH2: Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

HHB: List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.

IWU: Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.

JAF40:2330: Jim Duke's personal files

JAF41:1103: Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.

JAF43:2144: Yu, S.G., Anderson, P.J., and Elson, C.E. 1995. Efficacy of B-Ionone in the Chemoprevention of Rat Mammary Carcinogenesis. J. Agric. Food Chem. 43: 2144-2147.

JAF43:2283: J. Agric. Food Chem. 43: 2283.

JAF44:2802: Jim Duke's personal files

JAF45:3276: Jim Duke's personal files

JAF45:677: Jim Duke's personal files

JAF46:3434: Jim Duke's personal files

JAF47:4574: Jim Duke's personal files

JAF50:1389: Jim Duke's personal files

JAF50:4576: Jim Duke's personal files

JAF50:4586: Jim Duke's personal files

JAF51:2837: Jim Duke's personal files

JAF52:2507: Jim Duke's personal files

JAR10:7: Jim Duke's personal files

JAR12:99: Jim Duke's personal files

JAR4:22: J. Aromatherapy 4: 22.

JAR8:2: Jim Duke's personal files

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JE26:74: Jim Duke's personal files

JEO2:185: Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.

JFH33(6):569: J. Food Hyg. Soc. Jap. 33(6): 569.

JN127:668: Jim Duke's personal files

JNP39:446: Jim Duke's personal files

JNP49:5750: Jim Duke's personal files

JNP59:823: Jim Duke's personal files

JPP46:16: Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.

JSPR22:141: J. Stored. Prod. Res., 22:141, 1986.

JSPR22:141.1986: Jim Duke's personal files

KCH: Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.

LAF: Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.

LAF337: Jim Duke's personal files

LIP32:151: Jim Duke's personal files

LRN-JUN90: Lawrence Review of Natural Products, Jun-90.

LRN-SEP97: Lawrence Review of Natural Products, Sep-97.

M&R367: Jim Duke's personal files

M&R486: Jim Duke's personal files

M&R521: Jim Duke's personal files

M&R523: Jim Duke's personal files

M11: Merck 11th Edition

M29: Martindale's 29th

M29:1064: Jim Duke's personal files

MAD: Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.

MAR: Martindale's 28th

MED'95: Jim Duke's personal files

MIK: Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.

NIG: Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.

PJB1(2):266: Jim Duke's personal files

PJB1(3):242: Jim Duke's personal files

PR14:240: Jim Duke's personal files

PR14:303: Jim Duke's personal files

PR14:401: Jim Duke's personal files

RIE12:5: Revista Itiliana Eppos, 12: 5, 1994.

RIN: Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.

RJH: R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.

SHT158: Jim Duke's personal files

SZ44:183: Shoyakugaku Zasshi, 44: 183.

TEU: Jim Duke's personal files

TOX: Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.

W&W: Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)

WO2: Wealth of India.

X11281182: Jim Duke's personal files

X12495555: Jim Duke's personal files

X12537346: Jim Duke's personal files

X12587690: Jim Duke's personal files

X12615076: Jim Duke's personal files

X12637974: Jim Duke's personal files

X1438594: Jim Duke's personal files

X14506036: Jim Duke's personal files

X14703969: Jim Duke's personal files

X14998133: Jim Duke's personal files

X15598576: Jim Duke's personal files

X15778119: Jim Duke's personal files

X15862904: Jim Duke's personal files

X15931590: Jim Duke's personal files

X16248573: Jim Duke's personal files

X17199238: Jim Duke's personal files

X17686189: Jim Duke's personal files

X17867636: Jim Duke's personal files

X18072821: Jim Duke's personal files

X18409048: Jim Duke's personal files

X18484528: Jim Duke's personal files

X19876560: Jim Duke's personal files

X7199340: Jim Duke's personal files

X9242356: Jim Duke's personal files

ZEB: Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.

ppm = parts per million
tr = trace


Thu Feb 25 12:30:52 EST 2016