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Aspirin and colorectal cancer: the promise of precision chemoprevention

Identifier

020507

Type of Spiritual Experience

Background

A link has been provided to salicylic acid in order that you can find out the foods in which it is found.  Foods avoid some of the side effects of aspirin itself.

A description of the experience

Nat Rev Cancer. 2016 Feb 12. doi: 10.1038/nrc.2016.4. [Epub ahead of print]

Aspirin and colorectal cancer: the promise of precision chemoprevention.

Drew DA1, Cao Y2, Chan AT3.

1Massachusetts General Hospital and Harvard Medical School, Clinical and Translational Epidemiology Unit, 55 Fruit Street, Bartlett Ext. 9, Boston, Massachusetts 02114, USA.

2Massachusetts General Hospital and Harvard Medical School, Clinical and Translational Epidemiology Unit, and Harvard T.H. Chan School of Public Health, Department of Nutrition, 55 Fruit Street, Bartlett Ext. 9, Boston, Massachusetts 02114, USA.

3Massachusetts General Hospital and Harvard Medical School, Clinical and Translational Epidemiology Unit, Division of Gastroenterology, GRJ-825C, Boston, Massachusetts 02114, USA.

Abstract

Aspirin (acetylsalicylic acid) has become one of the most commonly used drugs, given its role as an analgesic, antipyretic and agent for cardiovascular prophylaxis. Several decades of research have provided considerable evidence demonstrating its potential for the prevention of cancer, particularly colorectal cancer. Broader clinical recommendations for aspirin-based chemoprevention strategies have recently been established; however, given the known hazards of long-term aspirin use, larger-scale adoption of an aspirin chemoprevention strategy is likely to require improved identification of individuals for whom the protective benefits outweigh the harms. Such a precision medicine approach may emerge through further clarification of aspirin's mechanism of action.

PMID:  26868177

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Cancer
Pain killers and NSAIDS

Suppressions

Salicylic acid

Commonsteps

References