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Parkinson’s disease and hypotension
Identifier
001106
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Characteristics of orthostatic hypotension in Parkinson's disease - Oka H, Yoshioka M, Onouchi K, Morita M, Mochio S, Suzuki M, Hirai T, Ito Y, Inoue K; Department of Neurology, Jikei University School of Medicine, 3-25-8, Nishi-shinbashi, Minato-ku, Tokyo, Japan.
Clinical symptoms of Parkinson's disease (PD) include not only motor distress but also autonomic dysfunction.
Orthostatic hypotension (OH) occurs in one-fifth to one-half of all patients with PD.
We examined the relation of this type of hypotension to clinical features ……… We performed HUT in 55 patients with PD and divided them into two groups according to the presence or absence of OH, defined as a drop in systolic blood pressure (SBP mmHg) by 20 mmHg or more on standing. ………..The results .. showed that 20 patients had OH and 35 did not.
The hypotension was associated with gender, older age, longer disease duration, posture and gait instability phenotype, low mini-mental state examination scores and visual hallucinations.
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