Some science behind the scenes
Obesity drugs other [releasing agents]
The vast majority of the drugs within this class of drugs have not produced any hallucinations, which is hardly surprising given that they are stimulants and stimulants do not generally produce spiritual experiences. The following provides a list of those for which no hallucinations could be found
- 4-MA - 4-Methylamphetamine (PAL-313; Aptrol) is a stimulant and anorectic drug of the amphetamine chemical classes. It acts as a potent serotonin, norepinephrine, and dopamine releasing agent
- Amfecloral also known as amphecloral is a stimulant drug of the amphetamine chemical class that was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed
- Amfepentorex is a stimulant drug derived from methamphetamine which is used as an appetite suppressant for the treatment of obesity. Dosage is 50–100 mg per day. Side effects include insomnia, hypertension and acute glaucoma
- Amfepramone ( other names diethylcathinone and diethylpropion, trade names Anorex, Linea, Nobesine, Prefamone, Regenon, Tepanil, Tenuate), is a stimulant drug that is used as an appetite suppressant
- Aminorex (Menocil, Apiquel, aminoxaphen, aminoxafen, McN-742) is an anorectic stimulant drug of the 2-amino-5-aryl oxazoline class. The drug has been retired from the marked after it was found to result in pulmonary hypertension.
- Amphetaminil (Aponeuron, AN-1) is a stimulant drug derived from amphetamine, which was developed in the 1970s and used for the treatment of obesity, ADHD, and narcolepsy. It has largely been withdrawn from clinical use following problems with abuse.
- Benzphetamine (Didrex) is an anorectic drug used as a short term adjunct in management of obesity.
- Clobenzorex (Asenlix, Dinintel, Finedal, Rexigen) is used as an appetite suppressant.
- Clominorex is related to aminorex and pemoline. It was developed as an appetite suppressant
- Clortermine (Voranil) is an anorectic drug of the amphetamine class
- Dimethylcathinone - [Metamfepramone, dimethylpropion, and dimepropion] is a stimulant drug of the amphetamine and cathinone classes. It was prescribed as an appetite suppressant and for the treatment of hypotension, but was never widely marketed. It was used as a recreational drug by Israelis under the name rafeket, but was made illegal in 2006
- Ethylamphetamine - Apetinil, Adiparthrol, etilamfetamine or N-ethylamphetamine, was invented in the early 1900s and was used as an appetite suppressant in the 1950s
- Fenfluramine - 3-trifluoromethyl-N-ethylamphetamine, trade names Pondimin, Ponderax and Adifax, is a drug that was part of the Fen-Phen anti-obesity medication (the other drug being phentermine). Fenfluramine was introduced on the U.S. market in 1973. It is a serotonin releasing agent. The drug was withdrawn from the U.S. market in 1997 after reports of heart valve disease, and pulmonary hypertension, including a condition known as cardiac fibrosis. After the US withdrawal of fenfluramine, it was also withdrawn from other markets around the world.
- Fenproporex (Perphoxene) is still used as an appetite suppressant for the treatment of obesity
- Fluminorex is related to other drugs such as aminorex and pemoline. It was developed as an appetite suppressant.
- Furfenorex - Frugalan, furfurylmethylamphetamine, was used as an appetite suppressant. It produces methamphetamine as a metabolite and is no longer marketed, due to possible problems with abuse.
- Mefenorex - Rondimen, Pondinil, Anexate was used as an appetite suppressant. It is an amphetamine derivative which was developed in the 1970s and used for the treatment of obesity. Mefenorex produces amphetamine as a metabolite.
- Phendimetrazine - (Bontril, Adipost, Anorex-SR, Appecon, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex) is used as an appetite suppressant
- Phenmetrazine (Preludin) was previously used as an appetite suppressant, but has since been withdrawn from the market. It is now rarely prescribed, due to concerns of abuse and addiction
- Thozalinone (Stimsen) has been used as an antidepressant in Europe and has also been trialed as an anorectic. It acts via inducing the release of norepinephrine and dopamine as with its analogues pemoline and aminorex
- Tiflorex, formerly known as flutiorex, is a stimulant amphetamine. Its most pronounced effect is in suppression of appetite
- Xylopropamine (Perhedrin, Esanin), also known as 3,4-dimethylamphetamine, is a stimulant, which was developed as an appetite suppressant in the 1950s. It was briefly sold, but was not widely marketed. The negative side effects - such as high blood pressure resulted in its discontinuation.
- Zylofuramine is a stimulant drug. It was developed in 1961, and was intended for use as an appetite suppressant and for the treatment of senile dementia in the elderly, but there is little information about it and it does not appear to have ever been marketed.