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E numbers and vaccines

E numbers, names and vaccines

This list shows all substances that have or had an E-number assigned AND which are also in vaccines. Not all additives listed are still allowed in the EU, but are listed as they used to have an E-number. The list was taken from Wikipedia mid 2014.  Using the List of Ingredients in vaccines – also on Wikipedia, I have provided a list of which vaccines according to them contain which E numbered products.

This list of vaccine ingredients indicates the culture media used in the production of common vaccines and the excipients they contain. Also listed are substances used in the manufacturing process. 

In some cases the name given by the manufacturer was so vague it was very difficult to home in on exact E number categories.  Furthermore there are excipients in vaccines that have no E number classification.  Thus this list needs to be used as a general guide – an indicator of the E numbers it might be wise to avoid if you have had a vaccination.

E100–E199 (colours)

Code

Name(s)

Use

Vaccine?

E101a

Riboflavin-5'-Phosphate

Yellow-orange

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E106

Riboflavin-5-Sodium Phosphate

Yellow

DTaP (Tripedia)

Hepatitis A vaccine (Havrix)

Zoster vaccine (Zostavax)

Varicella vaccine (Varivax)

Rotavirus vaccine (RotaTeq)

MMRV vaccine (ProQuad)

MMR vaccine (MMR-II)

Meningococcal vaccine (Menactra)

Influenza vaccine (Fluzone)

Influenza vaccine (Afluria)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E110

Sunset Yellow FCF (Orange Yellow S, FD&C Yellow 6)

Yellow-orange

Adenovirus vaccine

E170

Calcium carbonate, Chalk

White

Rotavirus vaccine (Rotarix)

E173

Aluminium

Silver to grey

Adenovirus vaccine

E223

Sodium metabisulphite

preservative

Japanese encephalitis vaccine (Ixiaro)

E231

Orthophenyl phenol

preservative

Vaccinia (ACAM2000)

Typhoid vaccine (inactivated – Typhim Vi)

Rabies vaccine (Imovax)

Pneumococcal vaccine (Pneumovax)

E232

Sodium orthophenyl phenol

preservative

Vaccinia (ACAM2000)

Typhoid vaccine (inactivated – Typhim Vi)

Rabies vaccine (Imovax)

Pneumococcal vaccine (Pneumovax)

E240

Formaldehyde

preservative

Anthrax vaccine (BioThrax)

DTaP (Daptacel)

DTaP (Infanrix)

DTaP (Tripedia)

DTaP/Hib (TriHIBit)

DTaP-IPV (Kinrix)

DTaP-HepB-IPV (Pediarix)

DtaP-IPV/Hib (Pentacel)

DT (diphtheria vaccine plus tetanus vaccine) (Sanofi)

DT (Massachusetts)

Hib vaccine (ACTHib)

Hib/Hep B (Comvax)

Hepatitis A vaccine (Havrix)

Tdap vaccine (Boostrix)

Tdap vaccine (Adacel)

Td vaccine (Mass)

Td vaccine (Decavac)

Polio vaccine (IPV - Ipol)

Meningococcal vaccine (Menveo)

Meningococcal vaccine (Menactra)

Japanese encephalitis vaccine (Ixiaro)

Japanese encephalitis vaccine (JE-Vax)

Influenza vaccine (Fluzone)

Influenza vaccine (Flulaval)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Recombivax)

Hepatitis A vaccine (Vaqta)

E300

Ascorbic acid (Vitamin C)

antioxidant

Typhoid vaccine (oral – Ty21a/Vivotif)

E304

Fatty acid esters of ascorbic acid (Ascorbyl palmitate)

antioxidant

Typhoid vaccine (oral – Ty21a/Vivotif)

E307

Alpha-tocopherol (synthetic)

antioxidant

Influenza vaccine (Flulaval)

Influenza vaccine (Fluarix)

 

E330

Citric acid

acid, acidity regulator

BCG (Bacillus Calmette-Guérin) (Tice)

E331

Sodium citrates (i) Monosodium citrate (ii) Disodium citrate (iii) Sodium citrate (trisodium citrate)

acidity regulator

Rotavirus vaccine (RotaTeq)

E339

Sodium phosphates (i) Monosodium phosphate (ii) Disodium phosphate (iii) Trisodium phosphate

antioxidant

Hepatitis A vaccine (Havrix)

Zoster vaccine (Zostavax)

Varicella vaccine (Varivax)

Varicella vaccine (Varivax)

Typhoid vaccine (inactivated – Typhim Vi)

Rotavirus vaccine (RotaTeq)

MMRV vaccine (ProQuad)

MMR vaccine (MMR-II)

Meningococcal vaccine (Menactra)

Influenza vaccine (Fluzone)

Influenza vaccine (Afluria)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E340

Potassium phosphates (i) Monopotassium phosphate (ii) Dipotassium phosphate (iii) Tripotassium phosphate

antioxidant

Adenovirus vaccine

BCG (Bacillus Calmette-Guérin) (Tice)

Hepatitis A vaccine (Havrix)

Zoster vaccine (Zostavax)

Varicella vaccine (Varivax)

Varicella vaccine (Varivax)

MMRV vaccine (ProQuad)

Meningococcal vaccine (Menactra)

Influenza vaccine (FluMist)

Influenza vaccine (Afluria)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E341

Calcium phosphates (i) Monocalcium phosphate (ii) Dicalcium phosphate (iii) Tricalcium phosphate

anti-caking agent, firming agent

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E342

Ammonium phosphates: (i) monoammonium phosphate (ii) diammonium phosphate

 

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Td vaccine (Mass)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E343

Magnesium phosphates (i) monomagnesium phosphate (ii) Dimagnesium phosphate

anti-caking agent

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E383

Calcium glycerylphosphate

acidity regulator

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E385

Calcium disodium ethylene diamine tetraacetate, (Calcium disodium EDTA)

sequestrant

Varicella vaccine (Varivax)

Influenza vaccine (FluMist)

E386

Disodium ethylene diamine tetraacetate (Disodium EDTA)

sequestrant

Varicella vaccine (Varivax)

Influenza vaccine (FluMist)

E408

Bakers yeast glycan

 

DTaP-HepB-IPV (Pediarix)

Hib/Hep B (Comvax)

Typhoid vaccine (oral – Ty21a/Vivotif)

Pneumococcal vaccine (Prevnar)

Meningococcal vaccine (Menveo)

Human papillomavirus (HPV) (Gardasil)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Recombivax)

Hepatitis B vaccine (Engerix-B)

E415

Xanthan gum (thickener)

stabiliser

Rotavirus vaccine (Rotarix)

E420

Sorbitol (i) Sorbitol (ii) Sorbitol syrup (emulsifier) (sweetener)

humectant

Yellow fever vaccine (YF-Vax)

Rotavirus vaccine (Rotarix)

MMRV vaccine (ProQuad)

MMR vaccine (MMR-II)

E421

Mannitol (anti-caking agent)

sweetener

Vaccinia (ACAM2000)

E426

Soybean hemicellulose

 

Adenovirus vaccine

Hib/Hep B (Comvax)

Hepatitis B vaccine (Recombivax)

E429

Peptones

 

DTaP (Tripedia)

Td vaccine (Decavac)

E432

Polyoxyethene (20) sorbitan monolaurate (polysorbate 20)

emulsifier

Hepatitis A vaccine (Havrix)

HepA/HepB vaccine (Twinrix)

E433

Polyoxyethene (20) sorbitan monooleate (polysorbate 80)

emulsifier

DTaP (Infanrix)

DTaP (Tripedia)

DTaP/Hib (TriHIBit)

DTaP-IPV (Kinrix)

DTaP-HepB-IPV (Pediarix)

DtaP-IPV/Hib (Pentacel)

Tdap vaccine (Boostrix)

Rotavirus vaccine (RotaTeq)

Pneumococcal vaccine (Prevnar)

Japanese encephalitis vaccine (JE-Vax)

Influenza vaccine (Flulaval)

Influenza vaccine (Fluarix)

Human papillomavirus (HPV) (Gardasil)

 

E441

Gelatine (emulsifier)

gelling agent

DTaP (Tripedia)

DTaP/Hib (TriHIBit)

Zoster vaccine (Zostavax)

Yellow fever vaccine (YF-Vax)

Varicella vaccine (Varivax)

Rabies vaccine (RabAvert)

MMRV vaccine (ProQuad)

MMR vaccine (MMR-II)

Japanese encephalitis vaccine (JE-Vax)

Influenza vaccine (FluMist)

Influenza vaccine (Fluzone)

E444

Sucrose acetate isobutyrate

emulsifier

Adenovirus vaccine

DTaP/Hib (TriHIBit)

Hib vaccine (ACTHib)

Varicella vaccine (Varivax)

Typhoid vaccine (oral – Ty21a/Vivotif)

Rotavirus vaccine (Rotarix)

Rotavirus vaccine (RotaTeq)

MMRV vaccine (ProQuad)

MMR vaccine (MMR-II)

E450

Diphosphates (i) Disodium diphosphate (ii) Trisodium diphosphate (iii) Tetrasodium diphosphate (iv) Dipotassium diphosphate (v) Tetrapotassium diphosphate (vi) Dicalcium diphosphate (vii) Calcium dihydrogen diphosphate

emulsifier

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Typhoid vaccine (inactivated – Typhim Vi)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E451

Triphosphates (i) Sodium triphosphate (pentasodium triphosphate) (ii) Pentapotassium triphosphate

emulsifier

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E452

Polyphosphates (i) Sodium polyphosphates (ii) Potassium polyphosphates (iii) Sodium calcium polyphosphate (iv) Calcium polyphosphates (v) Ammonium polyphosphate

emulsifier

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E460

Cellulose (i) Microcrystalline cellulose (ii) Powdered cellulose

emulsifier

Adenovirus vaccine

E461

Methyl cellulose

emulsifier

Adenovirus vaccine

E462

Ethyl cellulose

emulsifier

Adenovirus vaccine

E463

Hydroxypropyl cellulose

emulsifier

Adenovirus vaccine

E464

Hypromellose (hydroxypropyl methylcellulose)

emulsifier

Adenovirus vaccine

E465

Ethyl methyl cellulose

emulsifier

Adenovirus vaccine

E466

Carboxymethyl cellulose, Sodium carboxy methyl cellulose

emulsifier

Adenovirus vaccine

E467

Ethyl hydroxyethyl cellulose

 

Adenovirus vaccine

E468

Crosslinked sodium carboxymethyl cellulose (Croscarmellose)

emulsifier

Adenovirus vaccine

E469

Enzymically hydrolysed carboxymethylcellulose

emulsifier

Adenovirus vaccine

E472c

Citric acid esters of mono- and diglycerides of fatty acids

emulsifier

BCG (Bacillus Calmette-Guérin) (Tice)

E473

Sucrose esters of fatty acids

emulsifier

Adenovirus vaccine

DTaP/Hib (TriHIBit)

Typhoid vaccine (oral – Ty21a/Vivotif)

Rotavirus vaccine (RotaTeq)

MMRV vaccine (ProQuad)

E479b

Thermally oxidized soya bean oil interacted with mono- and diglycerides of fatty acids

emulsifier

Hib/Hep B (Comvax)

Hepatitis B vaccine (Recombivax)

E498

Partial polyglycerol esters of polycondensed fatty acids of castor oil

 

Adenovirus vaccine

E500

Sodium carbonates (i) Sodium carbonate (ii) Sodium bicarbonate (Sodium hydrogen carbonate) (iii) Sodium sesquicarbonate (acidity regulator)

raising agent

Adenovirus vaccine

MMRV vaccine (ProQuad)

E508

Potassium chloride (gelling agent)

seasoning

Zoster vaccine (Zostavax)

Varicella vaccine (Varivax)

MMRV vaccine (ProQuad)

Influenza vaccine (Afluria)

E509

Calcium chloride (sequestrant)

firming agent

Influenza vaccine (Afluria)

E517

Ammonium sulphate

acidity regulator

DTaP/Hib (TriHIBit)

Hib vaccine (ACTHib)

Tdap vaccine (Adacel)

Pneumococcal vaccine (Prevnar)

E520

Aluminium sulphate

firming agent

Adenovirus vaccine

E521

Aluminium sodium sulphate

firming agent

Adenovirus vaccine

E522

Aluminium potassium sulphate

acidity regulator

Adenovirus vaccine

DTaP (Tripedia)

DTaP/Hib (TriHIBit)

DT (diphtheria vaccine plus tetanus vaccine) (Sanofi)

Td vaccine (Decavac)

E523

Aluminium ammonium sulphate

acidity regulator

Adenovirus vaccine

DTaP (Tripedia)

DTaP/Hib (TriHIBit)

Hib vaccine (ACTHib)

Tdap vaccine (Adacel)

Pneumococcal vaccine (Prevnar)

E524

Sodium hydroxide

acidity regulator

Rotavirus vaccine (RotaTeq)

E540

Dicalcium diphosphate (acidity regulator)

emulsifier

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E541

Sodium aluminium phosphate (i) Acidic (ii) Basic

emulsifier

Adenovirus vaccine

DTaP (Daptacel)

DTaP-HepB-IPV (Pediarix)

DtaP-IPV/Hib (Pentacel)

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Tdap vaccine (Adacel)

Td vaccine (Mass)

Pneumococcal vaccine (Prevnar)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E542

Bone phosphate (Essentiale Calcium Phosphate, Tribasic)

anti-caking agent

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Hepatitis B vaccine (Engerix-B)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

E543

Calcium sodium polyphosphate

emulsifier

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E544

Calcium polyphosphate

emulsifier

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E545

Ammonium polyphosphate

emulsifier

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E554

Sodium aluminosilicate (sodium aluminium silicate)

anti-caking agent

Adenovirus vaccine

E555

Potassium aluminium silicate

anti-caking agent

Adenovirus vaccine

E556

Calcium aluminosilicate (calcium aluminium silicate)

anti-caking agent

Adenovirus vaccine

E559

Aluminium silicate (Kaolin)

anti-caking agent

Adenovirus vaccine

E572

Magnesium stearate, calcium stearate (emulsifier)

anti-caking agent

Adenovirus vaccine

E621

Monosodium glutamate (MSG)

flavour enhancer

Zoster vaccine (Zostavax)

Varicella vaccine (Varivax)

MMRV vaccine (ProQuad)

MMR vaccine (MMR-II)

Influenza vaccine (FluMist)

E622

Monopotassium glutamate

flavour enhancer

Varicella vaccine (Varivax)

Rabies vaccine (RabAvert)

MMR vaccine (MMR-II)

E623

Calcium diglutamate

flavour enhancer

Varicella vaccine (Varivax)

MMR vaccine (MMR-II)

E624

Monoammonium glutamate

flavour enhancer

Varicella vaccine (Varivax)

MMR vaccine (MMR-II)

E625

Magnesium diglutamate

flavour enhancer

Varicella vaccine (Varivax)

MMR vaccine (MMR-II)

E702

Chlortetracycline

antibiotic

Rabies vaccine (RabAvert)

E929

Acetone peroxide

 

Adenovirus vaccine

E955

Sucralose (Trichlorogalactosucrose)

sweetener

Adenovirus vaccine

DTaP/Hib (TriHIBit)

Zoster vaccine (Zostavax)

Varicella vaccine (Varivax)

Typhoid vaccine (oral – Ty21a/Vivotif)

Rotavirus vaccine (RotaTeq)

MMRV vaccine (ProQuad)

E1200

Polydextrose

stabiliser, thickening agent, humectant, carrier

Adenovirus vaccine

Hib/Hep B (Comvax)

Typhoid vaccine (oral – Ty21a/Vivotif)

Hepatitis B vaccine (Recombivax)

E1203

Polyvinyl alcohol

 

Adenovirus vaccine

E1410

Monostarch phosphate (stabiliser)

thickening agent

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E1412

Distarch phosphate esterified with sodium trimetasphosphate; esterified with phosphorus oxychloride (stabiliser)

thickening agent

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E1413

Phosphated distarch phosphate (stabiliser)

thickening agent

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E1414

Acetylated distarch phosphate (emulsifier)

thickening agent

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E1430

Distarch glycerine (stabiliser)

thickening agent

BCG (Bacillus Calmette-Guérin) (Tice)

Vaccinia (ACAM2000)

E1441

Hydroxy propyl distarch glycerine (stabiliser)

thickening agent

BCG (Bacillus Calmette-Guérin) (Tice)

Vaccinia (ACAM2000)

E1442

Hydroxy propyl distarch phosphate (stabiliser)

thickening agent

Hepatitis A vaccine (Havrix)

Varicella vaccine (Varivax)

Meningococcal vaccine (Menactra)

HepA/HepB vaccine (Twinrix)

Hepatitis B vaccine (Engerix-B)

E1452

Starch aluminium octenyl succinate

 

Adenovirus vaccine

E1503

Castor oil

resolving agent

Adenovirus vaccine

E1519

Benzyl alcohol

 

Adenovirus vaccine

E1525

Hydroxyethyl cellulose

thickening agent

Adenovirus vaccine