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Observations placeholder

Zemplar

Identifier

020396

Type of Spiritual Experience

Hallucination

Number of hallucinations: 10

Background

A description of the experience

Paricalcitol (chemically it is 19-nor-1,25-(OH)2-vitamin D2. Marketed under the trade name Zemplar) is a drug used for the prevention [sic] and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure. It is an analog of 1,25-dihydroxyergocalciferol, the active form of vitamin D2 (Ergocalciferol).

Adverse effects by frequency:
Very common (>10% frequency):

  • Nausea

Common (1-10% frequency):

  • Diarrhoea†
  • Oedema
  • Allergic reaction
  • Arthritis
  • Dizziness†
  • Stomach discomfort‡
  • Gastroesophageal reflux disease†
  • Acne†
  • Hypercalcaemia†
  • Hypocalcaemia†
  • Hyperphosphataemia
  • Decreased appetite†
  • Headache
  • Breast tenderness†
  • Taste changes
  • Hypoparathyroidism
  • Vertigo
  • Rash‡

Uncommon (0.1-1% frequency):

  • Abnormal hepatic enzymes‡
  • Constipation‡
  • Dry mouth‡
  • Itchiness‡
  • Hives
  • Hypersensitivity‡
  • Muscle spasms‡
  • Bleeding time prolonged
  • Aspartate aminotransferase increased
  • Laboratory test abnormal
  • Weight loss
  • Elevated blood creatinine
  • Cardiac arrest
  • Arrhythmia
  • Atrial flutter
  • Anaemia
  • Leucopenia
  • Lymphadenopathy
  • Coma
  • Stroke
  • Transient ischemic attack
  • Fainting
  • Myoclonus
  • Hypoaesthesia
  • Paraesthesia
  • Glaucoma
  • Conjunctivitis
  • Ear disorder
  • Pulmonary oedema
  • Asthma
  • Shortness of breath
  • Nose bleed
  • Cough
  • Rectal haemhorrhage
  • Colitis
  • Gastritis
  • Indigestion
  • Difficulty swallowing
  • Gastrointestinal disorder
  • Gastrointestinal haemorrhage
  • Bullous dermatitis
  • Hair loss
  • Hirsutism
  • Hyperhidrosis
  • Joint pain
  • Joint stiffness
  • Back pain
  • Muscle twitching
  • Muscle aches
  • Hyperparathyroidism
  • Hyperkalaemia
  • Hypocalcemia
  • Breast cancer
  • Sepsis
  • Pneumonia
  • Infection
  • Pharyngitis
  • Vaginal infection
  • Influenza
  • High blood pressure
  • Hypotension
  • Gait disturbance
  • Injection site pain
  • Fever
  • Chest pain
  • Condition aggravated
  • Muscle weakness
  • Malaise
  • Thirst
  • Breast pain
  • Impotence
  • Confusional state
  • Delirium
  • Depersonalization
  • Agitation
  • Insomnia
  • Nervousness

‡ These are adverse effects only seen in patients with grade 3 or 4 chronic kidney disease.

† These are adverse effects only seen in patients with grade 5 chronic kidney disease.

 On Jan, 14, 2017 11,821 people reported to have side effects when taking Zemplar.

Among them, 10 people (0.08%) have Hallucination

Time on Zemplar when people have Hallucination  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucination 0.00% 100.00% 0.00% 0.00% 0.00% 0.00% 0.00%

 

On Feb, 18, 2016: 4,351 people reported to have side effects when taking Zemplar. Among them, 208 people (4.78%) have Death.

Time on Zemplar when people have Death  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Death 37.84% 27.03% 21.62% 10.81% 2.70% 0.00% 0.00%

Gender of people who have Death when taking Zemplar  :

  Female Male
Death 45.63% 54.37%

Age of people who have Death when taking Zemplar  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Death 0.00% 0.00% 0.00% 0.00% 2.56% 1.71% 16.24% 79.49%

Top conditions involved for these people :

  1. Hyperparathyroidism secondary (60 people, 28.85%)
  2. Renal failure chronic (30 people, 14.42%)
  3. Hyperparathyroidism (23 people, 11.06%)

 

 

 

The source of the experience

eHealthme

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Commonsteps

References