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Observations placeholder

Stalevo and COMTan

Identifier

001527

Type of Spiritual Experience

Hallucination

Number of hallucinations: 498

Background

A description of the experience

Entacapone Entacapone is marketed under the trade name COMTan  in the United States. Stalevo  is another medication that contains entacapone in combination with carbidopa and levodopa (active ingredients in Sinemet).

Most common Comtan side effects from eHealthme

  • Fall - (220 reports)
  • Hallucinations - (214 reports)
  • Parkinson's disease - (186 reports)
  • Dyskinesia - (186 reports)
  • Drowsiness - (126 reports)
  • Fever - (125 reports)
  • Swallowing difficulty - (117 reports)
  • Pathological gambling - (117 reports)
  • Depression - (106 reports)
  • Drug ineffective - (105 reports)

Pharmacologically, entacapone is somewhat similar to carbidopa or benserazide, in that it is an inhibitor of an enzyme that converts L-DOPA into a compound that cannot cross the blood brain barrier. Entacapone is a member of the class of drugs known as nitrocatechols. The most frequent undesirable effects caused by entacapone relate to the increased effects of L-DOPA, such as involuntary movements (dyskinesias). These occur most frequently at the beginning of entacapone treatment. Others common side effects are gastrointestinal problems, including diarrhoea, nausea and abdominal pains. The substance may cause urine to turn reddish-brown. “This is a harmless side effect and is not a cause for concern” [sic].

On Jan, 31, 2017 2,702 people reported to have side effects when taking Comtan.  Among them, 214 people (7.92%) have Hallucination

On Feb, 02, 2017 2,702 people reported to have side effects when taking Comtan.  Among them, 13 people (0.48%) have Hallucination, Auditory

On Dec, 31, 20162,702 people reported to have side effects when taking Comtan.  Among them, 82 people (3.03%) have Hallucination, Visual

On Mar, 17, 2015: 3,073 people reported to have side effects when taking Stalevo 100. Among them, 189 people (6.15%) have Hallucination.

Time on Stalevo 100 when people have Hallucination  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucination 50.00% 15.38% 3.85% 3.85% 23.08% 3.85% 0.00%

Gender of people who have Hallucination when taking Stalevo 100  :

  Female Male
Hallucination 20.42% 79.58%

Age of people who have Hallucination when taking Stalevo 100  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Hallucination 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 7.18% 92.82%

Severity of Hallucination when taking Stalevo 100  :

  least moderate severe most severe
Hallucination 0.00% 0.00% 100.00% 0.00%

How people recovered from Hallucination  :

  while on the drug after off the drug not yet
Hallucination 0.00% 0.00% 100.00%

 

 

On Mar, 31, 2015: 3,073 people reported to have side effects when taking Stalevo 100. Among them, 175 people (5.69%) have Death.

Time on Stalevo 100 when people have Death  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Death 0.00% 50.00% 10.00% 10.00% 10.00% 20.00% 0.00%

The source of the experience

eHealthme

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Parkinsons disease drugs

Commonsteps

Hearing voices

References