Observations placeholder
Sensipar
Identifier
020027
Type of Spiritual Experience
Background
A description of the experience
Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues (Van Wagenen et al. (2001), U.S. Pat. 6,211,244). It is sold under the trade name Sensipar in North America and Australia and as Mimpara in Europe. Cinacalcet is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels), a consequence of end-stage renal disease. Cinacalcet is also indicated for the treatment of hypercalcemia in patients with parathyroid carcinoma Cinacalcet was FDA approved in March 2004, and was the first allosteric G protein-coupled receptor modulator to enter the pharmaceutical market. In 2014, cinacalcet was 76th out of the top 100 drugs in the list of largest selling pharmaceutical products.
Adverse effects
Common side effects of cinacalcet include:
- Stomach upset
- Vomiting
- Diarrhea
- Dizziness
- Nausea
- Weakness
- Chest pain
Clinical trials conducted in the United States by Amgen to determine whether the drug is safe for children were halted by the FDA in February 2013 following the death of a 14-year-old patient
Serious side effects, including overdose symptoms, of cinacalcet include:
- Burning
- Tingling
- Unusual feelings of the lips, tongue, fingers, or feet
- Muscle aches or cramps
- Sudden tightening of muscles in hands, feet, face, or throat
- Seizures
On Jan, 10, 2017 18,661 people reported to have side effects when taking Sensipar.
Among them, 35 people (0.19%) have Hallucination
Time on Sensipar when people have Hallucination :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Hallucination | 33.33% | 33.33% | 22.22% | 0.00% | 11.11% | 0.00% | 0.00% |
Gender of people who have Hallucination when taking Sensipar :
| Female | Male | |
| Hallucination | 43.75% | 56.25% |
Age of people who have Hallucination when taking Sensipar :
| 0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
| Hallucination | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 100.00% |
Severity of Hallucination when taking Sensipar :
| least | moderate | severe | most severe | |
| Hallucination | 0.00% | 0.00% | 0.00% | 100.00% |
How people recovered from Hallucination :
| while on the drug | after off the drug | not yet | |
| Hallucination | 0.00% | 0.00% | 100.00% |
On Jan, 11, 2016: 3,049 people reported to have side effects when taking Sensipar. Among them, 134 people (4.39%) have Death.
Time on Sensipar when people have Death :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Death | 23.81% | 9.52% | 0.00% | 42.86% | 23.81% | 0.00% | 0.00% |
Gender of people who have Death when taking Sensipar :
| Female | Male | |
| Death | 48.78% | 51.22% |
Age of people who have Death when taking Sensipar :
| 0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
| Death | 0.00% | 0.00% | 0.00% | 1.16% | 5.81% | 12.79% | 19.77% | 60.47% |