Observations placeholder
Rapamune, Rapamycin and Sirolimus
Identifier
015689
Type of Spiritual Experience
Background
A description of the experience
Sirolimus (also known as rapamycin) is a chemical that was discovered as a product of bacteria discovered on Easter Island (the island is also known as Rapa Nui). It was approved by the US Food and Drug Administration in September 1999 and is marketed under the trade name Rapamune.
Sirolimus was originally developed as an antifungal agent. However, this use was abandoned when it was discovered to have potent immunosuppressive and antiproliferative properties. It has since been shown to prolong the life of mice and might also be useful in the treatment of certain cancers.
The antiproliferative effect of sirolimus has also been used in conjunction with coronary stents to prevent restenosis in coronary arteries following balloon angioplasty. The sirolimus is formulated in a polymer coating that affords controlled release through the period following coronary intervention.
On Dec, 28, 2016 8,887 people reported to have side effects when taking Rapamune. Among them, 17 people (0.19%) have Hallucination
On Dec, 23, 2016 2,988 people reported to have side effects when taking Sirolimus. Among them, 6 people (0.2%) have Hallucination
On Jan, 15, 2017 2,988 people reported to have side effects when taking Sirolimus. Among them, 87 people (2.91%) have Death
On Dec, 12, 2016 8,887 people reported to have side effects when taking Rapamune.
Among them, 294 people (3.31%) have Death
Time on Rapamune when people have Death :
< 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
Death | 34.62% | 30.77% | 15.38% | 15.38% | 3.85% | 0.00% | 0.00% |
Gender of people who have Death when taking Rapamune :
Female | Male | |
Death | 27.54% | 72.46% |
Age of people who have Death when taking Rapamune :
0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
Death | 0.00% | 0.00% | 0.87% | 7.83% | 17.39% | 24.35% | 32.17% | 17.39% |
The source of the experience
eHealthmeConcepts, symbols and science items
Concepts
Symbols
Science Items
mTORsActivities and commonsteps
Activities
Overloads
Chemotherapy drugsEndothelial dysfunction
Fungal infection treatments
Heart failure and coronary heart disease
Immunosuppressants