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Coenzyme Q10, also known as ubiquinone, ubidecarenone, coenzyme Q, and abbreviated at times to CoQ10,  CoQ, or Q10 is a coenzyme that is ubiquitous in the bodies of most animals. It is a 1,4-benzoquinone, where Q refers to the quinone chemical group and 10 refers to the number of isoprenyl chemical subunits in its tail.

This oil-soluble, vitamin-like substance is present in most eukaryotic cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, which generates energy in the form of ATP. Ninety-five percent of the human body’s energy is generated this way. Therefore, those organs with the highest energy requirements—such as the heart, liver and kidney—have the highest CoQ10 concentrations.

CoQ10 is not approved by the US Food and Drug Administration (FDA) for the treatment of any medical condition. It is sold as a dietary supplement. In the US, supplements are not regulated as drugs but as foods. How CoQ10 is manufactured is not regulated and different batches and brands may vary significantly.

A 2004 laboratory analysis by ConsumerLab.com found CoQ10 supplements on the market did not all contain the quantity identified on the product label. Amounts varied from "no detectable CoQ10" to 75% of stated dose up to a 75% excess.

On Feb, 7, 2016: 2,565 people reported to have side effects when taking Q10. Among them, 8 people (0.31%) have Hallucination.

On Jan, 28, 2016: 2,565 people reported to have side effects when taking Q10. Among them, 36 people (1.40%) have Death.