Observations placeholder

Propolis and cancer

Identifier

005337

Type of Spiritual Experience

Background

A description of the experience

 

Folia Histochem Cytobiol. 2012 Apr 24;50(1):25-37. doi: 10.2478/18693. The anticancer activity of propolis. Sawicka D, Car H, Borawska MH, Nikli?ski J. Center of Experimental Medicine, Medical University of Bialystok, Poland.

Propolis and its compounds have been the subject of many studies due to their antimicrobial and antiinflammatory activity; however, it is now known that they also possess antitumor properties. This review aims to summarize the results of studies on the mechanism of activity of propolis and its active compounds such as CAPE and chrysin in the apoptotic process, and their influence on the proliferation of cancer cells. Our review shows that propolis and its presented compounds induce apoptosis pathways in cancer cells. The antiproliferative effects of propolis, CAPE or chrysin in cancer cells are the result of the suppression of complexes of cyclins, as well as cell cycle arrest. The results of in vitro and in vivo studies suggest that propolis, CAPE and chrysin may inhibit tumor cell progression and may be useful as potential chemotherapeutic or chemopreventive anticancer drugs.

PMID: 22532133

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Bacterial infection
Cancer
Viral infection

Suppressions

Bee propolis

Commonsteps

References